Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | PARL | Q9H300 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3286704 | 0.87 | PARL (0.60) | TSHRPARLPKMKMT2ASMN1; SMN2 | |
| SCHEMBL1493760 | 0.83 | PARL (0.56) | TSHRPARLPKMKMT2ASMN1; SMN2 | |
| SCHEMBL28177660 | 0.83 | PARL (0.56) | TSHRPARLPKMKMT2ASMN1; SMN2 | |
| SCHEMBL890525 | 0.83 | USP2 (0.48) | PKMKMT2ASMN1; SMN2POLBLMNA | |
| SCHEMBL3747944 | 0.81 | L3MBTL1 (0.57) | TSHRPARLKMT2ASMN1; SMN2POLB | |
| SCHEMBL1589535 | 0.79 | PARL (0.51) | PARLPKMKMT2AALDH1A1KDM4E | |
| Water SCHEMBL27582516 | 0.77 | PARL (0.50) | PARLPKMKMT2AALDH1A1KDM4E | |
| SCHEMBL9517667 | 0.77 | L3MBTL1 (0.43) | TSHRPARLKMT2APOLBALDH1A1 | |
| SCHEMBL27630329 | 0.76 | PARL (0.49) | PARLPKMKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL5960399 | 0.76 | POLB (0.80) | TSHRPKMKMT2ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102149699-A | Novel salt of morpholine derivative | ASTELLAS PHARMA INC | 2011-08-10 | — | — | CN | claimed |
| CN-102149386-A | Novel pharmaceutical composition for treating nociceptive pain | ASTELLAS PHARMA INC | 2011-08-10 | — | — | CN | claimed |
| CN-1950089-A | Morpholine compounds | PFIZER LTD (US) | 2007-04-18 | — | — | CN | claimed |
| EP-0252875-B1 | MICROBICIDAL AGENT | CIBA-GEIGY AG (CH) | 1993-01-27 | — | — | EP | claimed |
| CN-102149699-A | Novel salt of morpholine derivative | ASTELLAS PHARMA INC | 2011-08-10 | — | — | CN | disclosed |
| CN-1950089-A | Morpholine compounds | PFIZER LTD (US) | 2007-04-18 | — | — | CN | disclosed |
| US-5026719-A | Synergistic combination of triazole fungicide and morpholine alkylarylsulfonate | CIBA-GEIGY CORPORATION (US) | 1991-06-25 | — | — | US | disclosed |