SCHEMBL9517843

SCHEMBL9517843

Cc1csc2c(S)cnn12

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 1/20 0.35
MET P08581 1/20 0.35
LTK P29376 1/20 0.35
CDK9 P50750 1/20 0.35
PRKX P51817 1/20 0.35
LRRK2 Q5S007 1/20 0.35
CLK4 Q9HAZ1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8812071 0.62
SCHEMBL16785590 0.54 CHEK1 (0.66) CHEK1METLTKCDK9PRKX
SCHEMBL9517808 0.54 CHEK1 (0.41) CHEK1METLTKCDK9PRKX
SCHEMBL5044313 0.54 ALDH1A1 (0.34)
SCHEMBL10338953 0.52 CHEK1 (1.00) CHEK1METLTKCDK9PRKX
SCHEMBL6770348 0.52
SCHEMBL3459457 0.51 IDO1 (0.58) CHEK1METLTKCDK9PRKX
SCHEMBL9529947 0.47
SCHEMBL1541893 0.47
SCHEMBL13626763 0.47

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0238070-B1 Sulfonylurea compounds, their production and herbicidal use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1993-12-29 EP disclosed
US-5017212-A For rice paddies TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-05-21 US disclosed
EP-0238070-A2 Sulfonylurea compounds, their production and herbicidal use Takeda Chemical Industries, Ltd. (JP) 1987-09-23 EP disclosed