Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770378 | 0.89 | GPR55 (0.44) | — | |
| SCHEMBL9514367 | 0.83 | GAA (0.44) | — | |
| SCHEMBL9770383 | 0.83 | GPR55 (0.44) | — | |
| SCHEMBL12315224 | 0.79 | TYMS (0.47) | KMT2ASMN1; SMN2 | |
| SCHEMBL9514689 | 0.77 | CYP1A2 (0.45) | — | |
| SCHEMBL23271959 | 0.77 | ALDH1A1 (0.45) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17697658 | 0.76 | PDE3B (0.44) | SMN1; SMN2 | |
| SCHEMBL9749105 | 0.75 | — | — | |
| SCHEMBL340868 | 0.75 | GPR55 (0.46) | — | |
| SCHEMBL30004235 | 0.75 | TSHR (0.48) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511228-A4 | ESTERS OF 2-ARYLMETHYL-1-NAPHTHOL DERIVATIVES AS 5-LIPOXYGENASE INHIBITORS | — | 1993-04-21 | — | — | EP | disclosed |
| EP-0511228-A1 | ESTERS OF 2-ARYLMETHYL-1-NAPHTHOL DERIVATIVES AS 5-LIPOXYGENASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-11-04 | — | — | EP | disclosed |
| WO-1991010430-A1 | ESTERS OF 2-ARYLMETHYL-1-NAPHTHOL DERIVATIVES AS 5-LIPOXYGENASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-07-25 | — | — | WO | disclosed |
| US-5006555-A | Antiinflammatory, antithrombin, respiratory system disorder treatment | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-09 | — | — | US | disclosed |