SCHEMBL9518013

SCHEMBL9518013

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nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
TSHR P16473 2/20 0.34
LMNA P02545 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7372262 1.00 MEN1 (0.36) MEN1KMT2ATSHRLMNA
SCHEMBL33568 0.89 MEN1 (0.42) MEN1KMT2ATSHRLMNA
Ammonia Solution, Strong SCHEMBL21219103 0.87 MEN1 (0.41) MEN1KMT2ATSHRLMNA
SCHEMBL5485278 0.82 MEN1 (0.41) MEN1KMT2ATSHRLMNA
SCHEMBL9515464 0.79 MEN1 (0.38) MEN1KMT2ATSHRLMNA
SCHEMBL7373703 0.79 MEN1 (0.38) MEN1KMT2ATSHRLMNA
SCHEMBL5485284 0.74 ALDH1A1 (0.46) MEN1KMT2ATSHRLMNA
SCHEMBL20377338 0.73 TSHR (0.36) MEN1KMT2ATSHRLMNA
SCHEMBL22579203 0.73 TSHR (0.38) MEN1KMT2ATSHRLMNA
Hydrochloric Acid SCHEMBL6536992 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0379288-B1 Process and intermediates for isopropyl 3S-amino-2R-hydroxyalkanoates PFIZER (US) 1993-12-22 EP claimed