Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373703 | 1.00 | MEN1 (0.38) | MEN1KMT2ALMNAGAASMN1; SMN2 | |
| SCHEMBL33568 | 0.88 | MEN1 (0.42) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| Ammonia Solution, Strong SCHEMBL21219103 | 0.86 | MEN1 (0.41) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL27750849 | 0.81 | MEN1 (0.38) | MEN1KMT2ALMNAGAATSHR | |
| SCHEMBL5485278 | 0.81 | MEN1 (0.41) | MEN1KMT2ALMNATSHRMAPT | |
| SCHEMBL9518013 | 0.79 | MEN1 (0.36) | MEN1KMT2ALMNATSHR | |
| SCHEMBL7372262 | 0.79 | MEN1 (0.36) | MEN1KMT2ALMNATSHR | |
| SCHEMBL3288778 | 0.79 | LMNA (0.38) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL27750847 | 0.77 | LMNA (0.37) | MEN1KMT2ALMNATSHRMAPT | |
| SCHEMBL5485284 | 0.76 | ALDH1A1 (0.46) | MEN1KMT2ALMNASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379288-B1 | Process and intermediates for isopropyl 3S-amino-2R-hydroxyalkanoates | PFIZER (US) | 1993-12-22 | — | — | EP | claimed |