Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10542596 | 0.99 | ALDH1A1 (0.34) | MAOBALDH1A1MAPK1KMT2A | |
| SCHEMBL9518231 | 0.86 | ALDH1A1 (0.32) | MAOBALDH1A1MAPK1KMT2A | |
| Hydrochloric Acid SCHEMBL10538462 | 0.85 | ALDH1A1 (0.33) | ALDH1A1MAPK1KMT2A | |
| SCHEMBL9518257 | 0.79 | MAOB (0.31) | MAOBALDH1A1MAPK1KMT2A | |
| Hydrochloric Acid SCHEMBL9518627 | 0.78 | ALDH1A1 (0.32) | MAOBALDH1A1MAPK1KMT2A | |
| SCHEMBL9519552 | 0.74 | MAOB (0.31) | MAOB | |
| Hydrochloric Acid SCHEMBL9518424 | 0.74 | ALDH1A1 (0.31) | MAOBALDH1A1MAPK1KMT2A | |
| SCHEMBL9518460 | 0.72 | ALDH1A1 (0.41) | MAOBALDH1A1MAPK1KMT2A | |
| SCHEMBL9518484 | 0.70 | ALDH1A1 (0.31) | MAOBALDH1A1MAPK1KMT2A | |
| SCHEMBL12082569 | 0.69 | ADRA2A (0.55) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239306-B1 | TETRAHYDROCARBAZOLE ESTERS | MERCK FROSST CANADA INC. (CA) | 1993-06-02 | — | — | EP | claimed |
| EP-0269599-B1 | Substituted 1H-imidazoles | UCB SA (BE) | 1993-12-15 | — | — | EP | disclosed |
| EP-0269599-A2 | Substituted 1H-imidazoles | U C B, S.A. (BE) | 1988-06-01 | — | — | EP | disclosed |