Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9518932 | 0.83 | RORC (0.31) | — | |
| SCHEMBL6970351 | 0.69 | CYP2A6 (0.38) | — | |
| SCHEMBL31359403 | 0.68 | MEN1 (0.31) | KMT2AMEN1NPSR1 | |
| SCHEMBL6963771 | 0.68 | — | — | |
| SCHEMBL9521480 | 0.67 | TSHR (0.40) | TSHRUSP2ALDH1A1KMT2AGAA | |
| SCHEMBL7809080 | 0.63 | MAPT (0.34) | NPC1RAB9APKMNPSR1MAPT | |
| SCHEMBL12504656 | 0.61 | TSHR (0.43) | TSHRUSP2ALDH1A1KMT2AGAA | |
| SCHEMBL23879944 | 0.60 | ALDH1A1 (0.43) | TSHRUSP2ALDH1A1KMT2AGAA | |
| SCHEMBL12412399 | 0.60 | TSHR (0.40) | TSHRUSP2ALDH1A1KMT2AGAA | |
| SCHEMBL6959823 | 0.60 | CYP2A6 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0478729-A4 | PROCESS FOR MANUFACTURING ASPARTAME FROM A DIKETOPIPERAZINE AND NOVEL INTERMEDIATES AND DERIVATIVES THEREFOR | — | 1993-06-16 | — | — | EP | claimed |
| EP-0478729-A1 | PROCESS FOR MANUFACTURING ASPARTAME FROM A DIKETOPIPERAZINE AND NOVEL INTERMEDIATES AND DERIVATIVES THEREFOR. | NUTRASWEET CO (US) | 1992-04-08 | — | — | EP | claimed |
| WO-1991014378-A1 | PROCESS FOR MANUFACTURING ASPARTAME FROM A DIKETOPIPERAZINE AND NOVEL INTERMEDIATES AND DERIVATIVES THEREFOR | THE NUTRASWEET COMPANY (US) | 1991-10-03 | — | — | WO | claimed |
| EP-0478729-A4 | PROCESS FOR MANUFACTURING ASPARTAME FROM A DIKETOPIPERAZINE AND NOVEL INTERMEDIATES AND DERIVATIVES THEREFOR | — | 1993-06-16 | — | — | EP | disclosed |
| EP-0478729-A1 | PROCESS FOR MANUFACTURING ASPARTAME FROM A DIKETOPIPERAZINE AND NOVEL INTERMEDIATES AND DERIVATIVES THEREFOR. | NUTRASWEET CO (US) | 1992-04-08 | — | — | EP | disclosed |
| WO-1991014378-A1 | PROCESS FOR MANUFACTURING ASPARTAME FROM A DIKETOPIPERAZINE AND NOVEL INTERMEDIATES AND DERIVATIVES THEREFOR | THE NUTRASWEET COMPANY (US) | 1991-10-03 | — | — | WO | disclosed |