SCHEMBL9518564

SCHEMBL9518564

N#Cc1c(-c2cccc(Cl)c2)[nH]c(Cl)c1Cl

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 5/20 0.48
ADORA2A P29274 5/20 0.48
ADORA2B P29275 2/20 0.48
DYRK1A Q13627 1/20 0.47
KDM4E B2RXH2 2/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
GLA P06280 1/20 0.46
GAA P10253 1/20 0.46
HPGD P15428 1/20 0.46
HTT P42858 1/20 0.46
IDO1 P14902 1/20 0.45
TDO2 P48775 1/20 0.45
GRM5 P41594 3/20 0.44
ATM Q13315 1/20 0.43
NUDT1 P36639 1/20 0.41
MEN1 O00255 2/20 0.39
POLB P06746 2/20 0.39
KMT2A Q03164 2/20 0.39
MET P08581 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9226694 0.83 DYRK1A (0.59) ADORA1ADORA2ADYRK1AKDM4EALDH1A1
SCHEMBL10591192 0.81 MAPT (0.45) ADORA1DYRK1AKDM4EALDH1A1LMNA
SCHEMBL8070637 0.80 DYRK1A (0.44) DYRK1AKDM4EALDH1A1LMNAGLA
SCHEMBL10589586 0.79 IDO1 (0.42) DYRK1AKDM4EALDH1A1LMNAGLA
SCHEMBL7500352 0.79 IDO1 (0.44) ADORA1ADORA2ADYRK1ALMNAHPGD
SCHEMBL10333139 0.78 ADORA1 (0.47) ADORA1ADORA2ADYRK1AKDM4EALDH1A1
SCHEMBL9268713 0.75 DYRK1A (0.50) ADORA1ADORA2AADORA2BDYRK1AKDM4E
SCHEMBL28477518 0.75 ACMSD (0.64) ADORA1ADORA2AADORA2BKDM4EALDH1A1
SCHEMBL30051338 0.75 ACMSD (0.64) ADORA1ADORA2AADORA2BKDM4EALDH1A1
SCHEMBL10590224 0.75 DYRK1A (0.43) DYRK1APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0312723-B1 Method of and bait compositions for controlling mollusks AMERICAN CYANAMID CO (US) 1993-12-22 EP disclosed
US-5010098-A Arylpyrrole insecticidal acaricidal and nematicidal agents and methods for the preparation thereof AMERICAN CYANAMID COMPANY (US) 1991-04-23 US disclosed
US-4929634-A ARYLPYRROLE COMPOUNDS AMERICAN CYANAMID COMPANY (US) 1990-05-29 US disclosed
EP-0347488-A1 Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof AMERICAN CYANAMID COMPANY (US) 1989-12-27 EP disclosed
EP-0312723-A2 Method of and bait compositions for controlling mollusks AMERICAN CYANAMID COMPANY (US) 1989-04-26 EP disclosed