Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 5/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8781670 | 0.87 | IDO1 (0.44) | IDO1AHRCYP1B1DYRK1AKMO | |
| SCHEMBL9336072 | 0.85 | IDO1 (0.43) | IDO1AHRCYP1B1DYRK1AKMO | |
| SCHEMBL9226704 | 0.84 | MAPK14 (0.43) | IDO1AHRCYP1B1DYRK1AKMO | |
| SCHEMBL8070637 | 0.81 | DYRK1A (0.44) | IDO1DYRK1AMEN1KMT2AHTT | |
| SCHEMBL10589586 | 0.81 | IDO1 (0.42) | IDO1DYRK1AMEN1KMT2AHTT | |
| SCHEMBL8976164 | 0.80 | IDO1 (0.40) | IDO1AHRCYP1B1DYRK1AKMO | |
| SCHEMBL10590224 | 0.79 | DYRK1A (0.43) | DYRK1AMAPK14 | |
| SCHEMBL9518564 | 0.79 | ADORA1 (0.48) | IDO1DYRK1AMEN1KMT2AHTT | |
| SCHEMBL9518992 | 0.78 | DYRK1A (0.42) | IDO1DYRK1AMAPK14MEN1KMT2A | |
| SCHEMBL10591199 | 0.78 | PTGS2 (0.46) | IDO1DYRK1AMAPK14MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347488-B1 | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof | AMERICAN CYANAMID CO (US) | 1994-06-01 | — | — | EP | claimed |
| EP-0312723-B1 | Method of and bait compositions for controlling mollusks | AMERICAN CYANAMID CO (US) | 1993-12-22 | — | — | EP | claimed |
| US-5010098-A | Arylpyrrole insecticidal acaricidal and nematicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1991-04-23 | — | — | US | claimed |
| US-4929634-A | ARYLPYRROLE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1990-05-29 | — | — | US | claimed |
| EP-0347488-A1 | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1989-12-27 | — | — | EP | claimed |
| EP-0312723-A2 | Method of and bait compositions for controlling mollusks | AMERICAN CYANAMID COMPANY (US) | 1989-04-26 | — | — | EP | claimed |
| JP-1104042-A | — | — | None | — | — | JP | disclosed |
| JP-1135701-A | — | — | None | — | — | JP | disclosed |
| EP-0530515-B1 | Process for the preparation of N-halomethylpyrrole and intermediates | BASF AG (DE) | 2002-11-06 | — | — | EP | disclosed |
| EP-0492125-B1 | Insecticidal and synergistic miticidal compositions | AMERICAN CYANAMID CO (US) | 1997-08-27 | — | — | EP | disclosed |
| US-5591765-A | ARYLPYRROLECARBONITRILE | AMERICAN CYANAMID COMPANY (US) | 1997-01-07 | — | — | US | disclosed |
| US-5563279-A | Debrominative chlorination of pyrroles | AMERICAN CYANAMID COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| EP-0491136-B1 | Process for the manufacture of pesticidal 1-(alkoxymethyl)pyrrole compounds | AMERICAN CYANAMID CO (US) | 1996-09-18 | — | — | EP | disclosed |
| US-5010098-A | Arylpyrrole insecticidal acaricidal and nematicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1991-04-23 | — | — | US | disclosed |
| US-4929634-A | ARYLPYRROLE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| EP-0358047-A2 | Method of controlling phytopathogenic fungi | AMERICAN CYANAMID COMPANY (US) | 1990-03-14 | — | — | EP | disclosed |
| EP-0347488-A1 | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1989-12-27 | — | — | EP | disclosed |
| JP-H01135701-A | CONTROLL OF MOLLUSK AND BAIT COMPOSITION | AMERICAN CYANAMID CO | 1989-05-29 | — | — | JP | disclosed |
| EP-0312723-A2 | Method of and bait compositions for controlling mollusks | AMERICAN CYANAMID COMPANY (US) | 1989-04-26 | — | — | EP | disclosed |
| JP-H01104042-A | INSECTICIDAL, ACARICIDAL AND NEMATICIDAL ARAYLPYRROLE AND ITS PREPARATION | AMERICAN CYANAMID CO | 1989-04-21 | — | — | JP | disclosed |