Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | BCHE | P06276 | 2/20 | 0.62 |
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519818 | 0.98 | POLB (0.75) | POLBBCHEACHEALDH1A1DDAH1 | |
| SCHEMBL9521781 | 0.94 | POLB (0.72) | POLBBCHEACHEALDH1A1DDAH1 | |
| SCHEMBL9521547 | 0.87 | POLB (0.66) | POLBBCHEACHEDDAH1NPC1 | |
| SCHEMBL7856311 | 0.87 | POLB (0.96) | POLBDDAH1NPC1RAB9ANR2F2 | |
| SCHEMBL30701864 | 0.87 | POLB (0.96) | POLBDDAH1NPC1RAB9ANR2F2 | |
| SCHEMBL7856315 | 0.87 | POLB (0.96) | POLBDDAH1NPC1RAB9ANR2F2 | |
| SCHEMBL2331252 | 0.87 | POLB (0.96) | POLBDDAH1NPC1RAB9ANR2F2 | |
| SCHEMBL30701863 | 0.87 | POLB (0.96) | POLBDDAH1NPC1RAB9ANR2F2 | |
| SCHEMBL7854826 | 0.87 | POLB (0.96) | POLBDDAH1NPC1RAB9ANR2F2 | |
| SCHEMBL27835271 | 0.87 | POLB (0.96) | POLBDDAH1NPC1RAB9ANR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4026815-A | ADDING A PHOSPHONOCARBOXYLIC ACID AND A BENZIMIDAZOLE DERIVATIVE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-31 | — | — | US | claimed |
| US-4000079-A | ANTIFREEZE ADDITIVES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-28 | — | — | US | claimed |
| EP-0350467-B1 | Pharmacologically active benzimidazole derivatives | DOMPE FARMACEUTICI SPA (IT) | 1993-12-29 | — | — | EP | disclosed |
| US-4971980-A | ANTIHISTAMINES | DOMPE FARMACEUTICI S.P.A. (IT) | 1990-11-20 | — | — | US | disclosed |
| EP-0350467-A1 | Pharmacologically active benzimidazole derivatives | DOMPE' FARMACEUTICI S.p.A. (IT) | 1990-01-10 | — | — | EP | disclosed |
| EP-0226016-A1 | Process for inhibiting hydrogen-induced corrosion of metallic materials | BAYER AG (DE) | 1987-06-24 | — | — | EP | disclosed |
| US-4026815-A | ADDING A PHOSPHONOCARBOXYLIC ACID AND A BENZIMIDAZOLE DERIVATIVE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-31 | — | — | US | disclosed |
| US-4000079-A | ANTIFREEZE ADDITIVES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-28 | — | — | US | disclosed |