Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.61 |
| ▸ | BCHE | P06276 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521781 | 0.90 | POLB (0.72) | POLBDDAH1BCHENPC1RAB9A | |
| SCHEMBL9519818 | 0.89 | POLB (0.75) | POLBDDAH1BCHENPC1RAB9A | |
| SCHEMBL9518566 | 0.87 | POLB (0.73) | POLBDDAH1BCHENPC1RAB9A | |
| SCHEMBL230157 | 0.83 | POLB (0.84) | POLBDDAH1BCHENPC1RAB9A | |
| SCHEMBL4118942 | 0.82 | BCHE (0.69) | POLBDDAH1BCHENPC1RAB9A | |
| SCHEMBL135294 | 0.80 | POLB (0.72) | POLBDDAH1BCHENPC1RAB9A | |
| SCHEMBL29749508 | 0.80 | DDAH1 (0.72) | POLBDDAH1NPC1RAB9APDE10A | |
| SCHEMBL612507 | 0.80 | DDAH1 (0.72) | POLBDDAH1NPC1RAB9APDE10A | |
| SCHEMBL30677880 | 0.80 | POLB (0.72) | POLBDDAH1BCHENPC1RAB9A | |
| SCHEMBL10769383 | 0.80 | SMN1; SMN2 (0.60) | DDAH1BCHENPC1RAB9AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350467-B1 | Pharmacologically active benzimidazole derivatives | DOMPE FARMACEUTICI SPA (IT) | 1993-12-29 | — | — | EP | disclosed |
| US-4971980-A | ANTIHISTAMINES | DOMPE FARMACEUTICI S.P.A. (IT) | 1990-11-20 | — | — | US | disclosed |
| EP-0350467-A1 | Pharmacologically active benzimidazole derivatives | DOMPE' FARMACEUTICI S.p.A. (IT) | 1990-01-10 | — | — | EP | disclosed |
| EP-0226016-A1 | Process for inhibiting hydrogen-induced corrosion of metallic materials | BAYER AG (DE) | 1987-06-24 | — | — | EP | disclosed |