Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8468817 | 0.66 | AR (0.52) | ALDH1A1HTTKMT2AGLAHPGD | |
| SCHEMBL10939165 | 0.62 | AR (0.47) | ALDH1A1PDE7AAKR1C3AKR1C2CYP3A4 | |
| SCHEMBL31167302 | 0.60 | MAPT (0.50) | ALDH1A1KMT2AMAPTMEN1CRHBP | |
| SCHEMBL1361170 | 0.60 | CA1 (0.55) | ALDH1A1GAAKDM4EMAPTLMNA | |
| SCHEMBL22353110 | 0.60 | MAPT (0.56) | ALDH1A1KMT2AMAPTLMNAMEN1 | |
| SCHEMBL3845967 | 0.59 | GLA (0.42) | GAAGLAAKR1C3AKR1C2AR | |
| SCHEMBL1408443 | 0.59 | PDE7A (0.50) | ALDH1A1HTTKMT2AMAPTLMNA | |
| SCHEMBL31601785 | 0.59 | PDE7A (0.50) | ALDH1A1HTTKMT2AMAPTLMNA | |
| SCHEMBL19746948 | 0.59 | PDE7A (0.47) | ALDH1A1HTTKMT2ALMNAMEN1 | |
| SCHEMBL22353090 | 0.58 | ABCC8 (0.51) | ALDH1A1KMT2AMAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1026206-C | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for preparation thereof | AMERICAN CYANAMID CO (US) | 1994-10-19 | — | — | CN | disclosed |
| EP-0312723-B1 | Method of and bait compositions for controlling mollusks | AMERICAN CYANAMID CO (US) | 1993-12-22 | — | — | EP | disclosed |
| US-5010098-A | Arylpyrrole insecticidal acaricidal and nematicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1991-04-23 | — | — | US | disclosed |
| US-4929634-A | ARYLPYRROLE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| CN-1039807-A | Desinsection, kill mite, nematocides aryl-pyrrolidine and preparation method thereof | AMERICAN CYANAMID CO (US) | 1990-02-21 | — | — | CN | disclosed |
| EP-0347488-A1 | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1989-12-27 | — | — | EP | disclosed |
| EP-0312723-A2 | Method of and bait compositions for controlling mollusks | AMERICAN CYANAMID COMPANY (US) | 1989-04-26 | — | — | EP | disclosed |