Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730846 | 0.84 | ALDH1A1 (0.51) | HTTALDH1A1TDP1TSHRMEN1 | |
| SCHEMBL95714 | 0.83 | CYP1A2 (0.54) | POLBHTTALDH1A1TDP1TSHR | |
| SCHEMBL16126092 | 0.81 | HSD17B10 (0.51) | POLBALDH1A1TDP1MEN1MAPT | |
| SCHEMBL7566464 | 0.81 | POLB (0.59) | POLBHTTALDH1A1TDP1TSHR | |
| SCHEMBL24519723 | 0.78 | CYP19A1 (0.44) | HTTALDH1A1CYP19A1MAPT | |
| SCHEMBL9518662 | 0.78 | POLB (0.45) | POLBHTTALDH1A1TDP1TSHR | |
| SCHEMBL28113258 | 0.76 | POLB (0.50) | POLBHTTALDH1A1TDP1MAPT | |
| SCHEMBL9732283 | 0.76 | KAT2B (0.42) | POLBHTTALDH1A1TDP1MEN1 | |
| SCHEMBL11317000 | 0.76 | HTT (0.49) | POLBHTTALDH1A1TDP1TSHR | |
| SCHEMBL28218218 | 0.75 | POLB (0.52) | POLBHTTALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331394-B1 | PROCESS FOR PREPARING 2 BETA-SUBSTITUTED-METHYLPENICILLIN DERIVATIVES | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-4898939-A | Process for preparing 2β-substituted-methylpenicillin derivatives | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1990-02-06 | — | — | US | disclosed |
| EP-0331394-A1 | Process for preparing 2 beta-substituted-methylpenicillin derivatives | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1989-09-06 | — | — | EP | disclosed |