Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CRHBP | P24387 | 3/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9518671 | 0.84 | POLB (0.45) | ALDH1A1TSHRTDP1CYP3A4MAPT | |
| SCHEMBL95714 | 0.83 | CYP1A2 (0.54) | ALDH1A1TSHRTDP1MAPTMEN1 | |
| SCHEMBL16126092 | 0.81 | HSD17B10 (0.51) | ALDH1A1TDP1CYP3A4MAPTMEN1 | |
| SCHEMBL14894155 | 0.79 | ALDH1A1 (0.56) | ALDH1A1TSHRTDP1CYP3A4MAPT | |
| SCHEMBL25378334 | 0.78 | ALDH1A1 (0.51) | ALDH1A1TSHRTDP1CYP3A4MAPT | |
| SCHEMBL9730842 | 0.78 | ALDH1A1 (0.51) | ALDH1A1TSHRTDP1CYP3A4MAPT | |
| SCHEMBL28226713 | 0.78 | ALDH1A1 (0.51) | ALDH1A1TSHRTDP1CYP3A4MAPT | |
| SCHEMBL11188405 | 0.78 | ALDH1A1 (0.64) | ALDH1A1TSHRTDP1CYP3A4MAPT | |
| SCHEMBL10139118 | 0.78 | ALDH1A1 (0.64) | ALDH1A1TSHRTDP1CYP3A4MAPT | |
| SCHEMBL1827226 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272016-B1 | 2BETA-SUBSTITUTED-METHYLPENICILLANIC ACID DERIVATIVES, AND SALTS AND ESTERS THEREOF | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1992-04-08 | — | — | EP | disclosed |
| EP-0273599-B1 | PROCESS FOR PREPARING 2BETA-SUBSTITUTED-METHYL-PENICILLIN DERIVATIVES | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1992-04-01 | — | — | EP | disclosed |
| US-4933444-A | Process for preparing 2β-substituted-methylpenicillin derivatives | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |
| US-4891369-A | BETA-LACTAMASE INHIBITORS | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1990-01-02 | — | — | US | disclosed |
| EP-0273599-A1 | Process for preparing 2beta-substituted-methyl-penicillin derivatives | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1988-07-06 | — | — | EP | disclosed |
| EP-0272016-A1 | 2beta-substituted-methylpenicillanic acid derivatives, and salts and esters thereof | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1988-06-22 | — | — | EP | disclosed |