Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.68 |
| ▸ | NAAA | Q02083 | 1/20 | 0.63 |
| ▸ | FAAH | O00519 | 3/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502450 | 0.98 | CASP2 (0.71) | CASP2NAAAFAAHEPHX2EPHX1 | |
| SCHEMBL1146790 | 0.98 | CASP2 (0.71) | CASP2NAAAFAAHEPHX2EPHX1 | |
| SCHEMBL9518701 | 0.98 | CASP2 (0.71) | CASP2NAAAFAAHEPHX2EPHX1 | |
| SCHEMBL21779474 | 0.94 | CASP2 (0.61) | CASP2NAAAFAAHEPHX2HPGD | |
| SCHEMBL2616429 | 0.94 | CASP2 (0.67) | CASP2NAAAFAAHEPHX2EPHX1 | |
| SCHEMBL12523062 | 0.94 | CASP2 (0.59) | CASP2NAAAFAAHEPHX2EPHX1 | |
| SCHEMBL25922800 | 0.93 | CASP2 (0.65) | CASP2NAAAFAAHEPHX2EPHX1 | |
| SCHEMBL23394708 | 0.91 | CASP2 (0.62) | CASP2NAAAFAAHEPHX2EPHX1 | |
| SCHEMBL12192205 | 0.91 | CASP2 (0.62) | CASP2NAAAFAAHEPHX2EPHX1 | |
| SCHEMBL2616294 | 0.90 | CASP2 (0.55) | CASP2NAAAFAAHEPHX2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410726-B1 | S-SUBSTITUTED BETA-THIOACRYLAMIDES AND THEIR USE AS MICROBICIDES | ROHM AND HAAS COMPANY (US) | 1993-09-01 | — | — | EP | disclosed |
| US-5118681-A | Bactericides | ROHM AND HAAS COMPANY (US) | 1992-06-02 | — | — | US | disclosed |
| EP-0410726-A1 | S-substituted beta-thioacrylamides and their use as microbicides | ROHM AND HAAS COMPANY (US) | 1991-01-30 | — | — | EP | disclosed |