Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 3/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12523062 | 0.96 | CASP2 (0.59) | CASP2HPGDNAAAFAAHCNR1 | |
| SCHEMBL2616429 | 0.93 | CASP2 (0.67) | CASP2NAAAFAAHDNM1EPHX2 | |
| SCHEMBL9518772 | 0.90 | CASP2 (0.68) | CASP2HPGDNAAAFAAHDNM1 | |
| SCHEMBL9502450 | 0.89 | CASP2 (0.71) | CASP2NAAAFAAHDNM1EPHX2 | |
| SCHEMBL9518701 | 0.89 | CASP2 (0.71) | CASP2NAAAFAAHDNM1EPHX2 | |
| SCHEMBL1146790 | 0.89 | CASP2 (0.71) | CASP2NAAAFAAHDNM1EPHX2 | |
| SCHEMBL19652721 | 0.87 | CASP2 (0.50) | CASP2HPGDNAAAFAAHCNR1 | |
| SCHEMBL17736080 | 0.87 | CASP2 (0.53) | CASP2HPGDNAAAFAAHCNR1 | |
| SCHEMBL21779474 | 0.85 | CASP2 (0.61) | CASP2HPGDNAAAFAAHCNR1 | |
| SCHEMBL25922800 | 0.84 | CASP2 (0.65) | CASP2NAAAFAAHDNM1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170924-B1 | 5-BROMO-2'-DEOXY-URIDINE LABELED NUCLEOTIDE TRIPHOSPHATES AND NUCLEIC ACID PROBES AND METHODS OF MAKING AND USING THE SAME | LIFE TECHNOLOGIES CORP (US) | 2015-07-22 | — | — | EP | disclosed |
| US-20120252030-A1 | 5-BROMO-2'-DEOXY-URIDINE LABELED NUCLEOTIDE TRIPHOSPHATES AND NUCLEIC ACID PROBES AND METHODS OF MAKING AND USING THE SAME | Life Technologies Corporation (US) | 2012-10-04 | — | — | US | disclosed |
| US-8163897-B2 | 5-bromo-2′-deoxy-uridine labeled nucleotide triphosphates and nucleic acid probes and methods of making and using the same | APPLIED BIOSYSTEMS, LLC (US) | 2012-04-24 | — | — | US | disclosed |
| US-20110207920-A1 | 5-BROMO-2'-DEOXY-URIDINE LABELED NUCLEOTIDE TRIPHOSPHATES AND NUCLEIC ACID PROBES AND METHODS OF MAKING AND USING THE SAME | Life Technologies Corporation (US) | 2011-08-25 | — | — | US | disclosed |
| US-7915392-B2 | 5-bromo-2′-deoxy-uridine labeled nucleotide triphosphates and nucleic acid probes and methods of making and using the same | Life Technologies Corporation (US) | 2011-03-29 | — | — | US | disclosed |
| US-7915392-B2 | 5-bromo-2′-deoxy-uridine labeled nucleotide triphosphates and nucleic acid probes and methods of making and using the same | Life Technologies Corporation (US) | 2011-03-29 | — | — | US | disclosed |
| US-20090325158-A1 | 5-Bromo-2'-Deoxy-Uridine Labeled Nucleotide Triphosphates and Nucleic Acid Probes and Methods of Making and Using the Same | APPLERA CORPORATION (US) | 2009-12-31 | — | — | US | disclosed |
| US-20090325158-A1 | 5-Bromo-2'-Deoxy-Uridine Labeled Nucleotide Triphosphates and Nucleic Acid Probes and Methods of Making and Using the Same | APPLERA CORPORATION (US) | 2009-12-31 | — | — | US | disclosed |
| WO-2008157311-A2 | 5-BROMO-2'-DEOXY-URIDINE LABELED NUCLEOTIDE TRIPHOSPHATES AND NUCLEIC ACID PROBES AND METHODS OF MAKING AND USING THE SAME | APPLERA CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207920-A1 | 5-BROMO-2'-DEOXY-URIDINE LABELED NUCLEOTIDE TRIPHOSPHATES AND NUCLEIC ACID PROBES AND METHODS OF MAKING AND USING THE SAME | DUT, PCNA, TK1 | CASP2 973/4885HPGD 670/4885NAAA 640/4885 |
| US-20090325158-A1 | 5-Bromo-2'-Deoxy-Uridine Labeled Nucleotide Triphosphates and Nucleic Acid Probes and Methods of Making and Using the Same | DUT, PCNA, TK1 | CASP2 973/4885HPGD 670/4885NAAA 640/4885 |
| US-20120252030-A1 | 5-BROMO-2'-DEOXY-URIDINE LABELED NUCLEOTIDE TRIPHOSPHATES AND NUCLEIC ACID PROBES AND METHODS OF MAKING AND USING THE SAME | DUT, PCNA, TK1 | CASP2 973/4885HPGD 670/4885NAAA 640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.