Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KCNN4 | O15554 | 10/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.39 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1244297 | 0.86 | CYP1A2 (0.65) | CYP1A2MAPTKMT2AKCNN4CYP2D6 | |
| SCHEMBL21682397 | 0.83 | MAPT (0.53) | CYP1A2MAPTKMT2AKCNN4HTT | |
| SCHEMBL11842568 | 0.79 | CYP1A2 (0.70) | CYP1A2MAPTKMT2AKCNN4HTT | |
| SCHEMBL27485211 | 0.78 | CYP1A2 (0.56) | CYP1A2MAPTKMT2AKCNN4CYP2D6 | |
| SCHEMBL4377323 | 0.78 | CYP1A2 (0.50) | CYP1A2MAPTKMT2AKCNN4HTT | |
| SCHEMBL4556174 | 0.77 | MAPT (0.56) | CYP1A2MAPTKMT2AKCNN4HTT | |
| SCHEMBL28993126 | 0.77 | CYP1A2 (0.54) | CYP1A2MAPTTSHRPOLBCYP3A4 | |
| SCHEMBL7593594 | 0.76 | MAPT (0.54) | CYP1A2MAPTKMT2AKCNN4HTT | |
| SCHEMBL9211554 | 0.76 | MAPT (0.54) | CYP1A2MAPTKMT2AKCNN4HTT | |
| SCHEMBL1817185 | 0.74 | MAPT (0.63) | CYP1A2MAPTKMT2AKCNN4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335046-B1 | Method for producing 2,4-dihydroxyquinoline derivatives | MITSUBISHI CHEM IND (JP) | 1993-12-01 | — | — | EP | disclosed |
| US-4904787-A | CYCLIZATION USING POLYPHOSPHORIC ACID; NONHYDROLIZING, ONE STEP | MITSUBISHI KASEI CORPORATION (JP) | 1990-02-27 | — | — | US | disclosed |
| EP-0335046-A1 | Method for producing 2,4-dihydroxyquinoline derivatives | MITSUBISHI KASEI CORPORATION (JP) | 1989-10-04 | — | — | EP | disclosed |