SCHEMBL1817185

SCHEMBL1817185

CC(Cl)(C(N)=O)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.63
KMT2A Q03164 1/20 0.63
CYP1A2 P05177 2/20 0.50
KCNN4 O15554 7/20 0.46
CYP2C19 P33261 1/20 0.45
HIF1A Q16665 1/20 0.45
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
HDAC9 Q9UKV0 1/20 0.44
HDAC5 Q9UQL6 1/20 0.44
HTT P42858 1/20 0.43
CYP2D6 P10635 2/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL305060 0.82 CYP1A2 (0.60) MAPTKMT2ACYP1A2KCNN4CYP2C19
SCHEMBL29613223 0.82 CYP1A2 (0.60) MAPTKMT2ACYP1A2KCNN4CYP2C19
SCHEMBL16753453 0.82 CYP1A2 (0.60) MAPTKMT2ACYP1A2KCNN4CYP2C19
SCHEMBL11715049 0.82 CYP1A2 (0.54) MAPTKMT2ACYP1A2KCNN4CYP2C19
SCHEMBL7255208 0.80 CYP1A2 (0.52) MAPTKMT2ACYP1A2KCNN4CYP2C19
SCHEMBL11842568 0.79 CYP1A2 (0.70) MAPTKMT2ACYP1A2KCNN4CYP2C19
SCHEMBL9710789 0.79 HDAC3 (0.50) MAPTKMT2ACYP1A2KCNN4CYP2C19
SCHEMBL4778710 0.79 MAPT (0.59) MAPTKMT2ACYP1A2KCNN4CYP2C19
SCHEMBL5552907 0.78 CYP1A2 (0.50) MAPTKMT2ACYP1A2KCNN4CYP2C19
SCHEMBL368343 0.77 MAPT (1.00) MAPTKMT2ACYP1A2KCNN4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5320096-A None JP disclosed
US-11746178-B2 Polymer production method and radical polymerization initiating group-containing compound DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2023-09-05 US disclosed
US-11746178-B2 Polymer production method and radical polymerization initiating group-containing compound DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2023-09-05 US disclosed
US-10982033-B2 Polymer production method and radical polymerization initiating group-containing compound DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2021-04-20 US disclosed
US-20190002619-A1 POLYMER PRODUCTION METHOD AND RADICAL POLYMERIZATION INITIATING GROUP-CONTAINING COMPOUND DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2019-01-03 US disclosed
US-7947712-B2 Antiarthritic agents; asthma; chronic obstructive pulminary diosrders; atherosclerosis; vision defects; hepatitis; central nervous system disorders; cardiovascular disorders; wound healing agents; restenosis; cirrhosis; multiple sclerosis; glomerulonephritis; graft versus host disease; antidiabetic agent WYETH LLC (US) 2011-05-24 US disclosed
US-20080269213-A1 8-Hydroxyquinoline compounds and methods thereof WYETH (US) 2008-10-30 US disclosed
WO-2008016676-A2 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS CYTOKINETICS, INCORPORATED (US) 2008-02-07 WO disclosed
JP-H05320096-A PRODUCTION OF GLYCOLLIC ACIDS NIPPON SYNTHETIC CHEM IND CO LTD:THE 1993-12-03 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080269213-A1 8-Hydroxyquinoline compounds and methods thereof MMP8, MMP26, MMP9 MAPT 2414/4885KMT2A 4052/4885CYP1A2 763/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.