Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9518835 | 1.00 | MEN1 (0.38) | MEN1KMT2ALMNAHTTNPSR1 | |
| Oxalic Acid SCHEMBL9613749 | 0.79 | SCN4A (0.39) | MEN1KMT2ALMNAHTTNPSR1 | |
| Oxalic Acid SCHEMBL9518842 | 0.75 | KCNJ11 (0.38) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| Oxalic Acid SCHEMBL9614031 | 0.74 | KMT2A (0.52) | MEN1KMT2AMCL1KDM4EALDH1A1 | |
| Oxalic Acid SCHEMBL9517855 | 0.74 | KMT2A (0.48) | KMT2AMCL1CYP1A2KDM4EALDH1A1 | |
| Oxalic Acid SCHEMBL9517848 | 0.74 | KMT2A (0.48) | KMT2AMCL1CYP1A2KDM4EALDH1A1 | |
| Oxalic Acid SCHEMBL9518051 | 0.72 | KMT2A (0.42) | MEN1KMT2ALMNAMCL1CYP1A2 | |
| Oxalic Acid SCHEMBL9518042 | 0.72 | KMT2A (0.42) | MEN1KMT2ALMNAMCL1CYP1A2 | |
| SCHEMBL10484268 | 0.68 | MCL1 (0.35) | MEN1KMT2AHTTMAPTSMN1; SMN2 | |
| SCHEMBL21010165 | 0.68 | CYP2C9 (0.49) | MEN1KMT2ALMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318234-B1 | IMPROVEMENTS IN OR RELATING TO SELECTIVE SEROTONIN UPTAKE INHIBITORS | ELI LILLY AND COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4876282-A | ANTIDEPRESSANT, DIETETICS, ANTIALCOHOLISM AGENT | ELI LILLY AND COMPANY (US) | 1989-10-24 | — | — | US | disclosed |