Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ADA | P00813 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9518051 | 1.00 | KMT2A (0.42) | KMT2AMEN1MTNR1AMCL1TDP1 | |
| Oxalic Acid SCHEMBL9517855 | 0.89 | KMT2A (0.48) | KMT2AMTNR1AMCL1TDP1SLC1A3 | |
| Oxalic Acid SCHEMBL9517848 | 0.89 | KMT2A (0.48) | KMT2AMTNR1AMCL1TDP1SLC1A3 | |
| SCHEMBL9518025 | 0.82 | SIGMAR1 (0.46) | MTNR1AMCL1TDP1SLC1A3SLC1A2 | |
| Oxalic Acid SCHEMBL9614065 | 0.79 | KMT2A (0.53) | KMT2AMEN1MCL1TDP1 | |
| SCHEMBL1702547 | 0.74 | IDO1 (0.48) | KMT2AMEN1IDO1 | |
| SCHEMBL5322260 | 0.74 | SLC1A3 (0.51) | KMT2AMTNR1AMCL1TDP1SLC1A3 | |
| Oxalic Acid SCHEMBL9518056 | 0.74 | MEN1 (0.52) | KMT2AMEN1MTNR1AMCL1TDP1 | |
| SCHEMBL8329891 | 0.74 | MTNR1A (0.44) | MTNR1ATDP1SLC1A3SLC1A2SLC1A1 | |
| Oxalic Acid SCHEMBL9519031 | 0.73 | OPRM1 (0.48) | KMT2AMTNR1AMCL1TDP1METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318234-B1 | IMPROVEMENTS IN OR RELATING TO SELECTIVE SEROTONIN UPTAKE INHIBITORS | ELI LILLY AND COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| EP-0211721-B1 | PHENYLETHANOL AMINOTETRALINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI S.A. (FR) | 1989-10-04 | — | — | EP | disclosed |
| EP-0318234-A2 | Improvements in or relating to selective serotonin uptake inhibitors | ELI LILLY AND COMPANY (US) | 1989-05-31 | — | — | EP | disclosed |