Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9518984 | 1.00 | ALOX15 (0.47) | ALOX15TSHRERCC5FEN1CYP19A1 | |
| SCHEMBL6489191 | 0.95 | MAPT (0.43) | ALOX15TSHRERCC5FEN1CYP19A1 | |
| SCHEMBL6489175 | 0.95 | MAPT (0.43) | ALOX15TSHRERCC5FEN1CYP19A1 | |
| SCHEMBL23934177 | 0.83 | ALDH1A1 (0.47) | ALOX15TSHRERCC5FEN1CYP19A1 | |
| SCHEMBL5491615 | 0.82 | CES1 (0.50) | ALOX15TSHRERCC5FEN1CYP19A1 | |
| SCHEMBL6497142 | 0.81 | HTT (0.46) | ALDH1A1KDM4EPOLBGAACTDSP1 | |
| SCHEMBL6497138 | 0.81 | HTT (0.46) | ALDH1A1KDM4EPOLBGAACTDSP1 | |
| SCHEMBL18143857 | 0.81 | TPMT (0.47) | ERCC5FEN1ALDH1A1GAAMAPT | |
| SCHEMBL18143864 | 0.81 | TPMT (0.47) | ERCC5FEN1ALDH1A1GAAMAPT | |
| SCHEMBL3250292 | 0.79 | CA1 (0.53) | CYP19A1POLBCES2CES1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369762-B1 | Pesticides | ROUSSEL UCLAF (FR) | 1993-12-29 | — | — | EP | disclosed |
| US-5202356-A | Insecticides, miticides | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-04-13 | — | — | US | disclosed |
| EP-0369762-A1 | Pesticides | ROUSSEL-UCLAF (FR) | 1990-05-23 | — | — | EP | disclosed |