Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15669931 | 0.74 | MAPT (0.48) | LMNAADORA3KMT2AALDH1A1MAPT | |
| Methane SCHEMBL11336749 | 0.74 | MAPT (0.48) | LMNAADORA3KMT2AALDH1A1MAPT | |
| SCHEMBL1895535 | 0.74 | MAPT (0.48) | LMNAADORA3KMT2AALDH1A1MAPT | |
| SCHEMBL1894049 | 0.74 | MAPT (0.48) | LMNAADORA3KMT2AALDH1A1MAPT | |
| SCHEMBL5358122 | 0.71 | HDAC8 (0.43) | ALDH1A1GAA | |
| Naphthalene SCHEMBL28102989 | 0.70 | MAPT (0.46) | LMNAADORA3KMT2AALDH1A1MAPT | |
| SCHEMBL10541313 | 0.68 | TNKS2 (0.46) | LMNAADORA3KMT2AALDH1A1MAPT | |
| SCHEMBL10153082 | 0.66 | LMNA (0.41) | LMNAADORA3KMT2AALDH1A1MAPT | |
| SCHEMBL29990763 | 0.65 | SMN1; SMN2 (0.36) | LMNAADORA3KMT2AUSP2MEN1 | |
| SCHEMBL10042832 | 0.64 | LMNA (0.40) | LMNAADORA3KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254578-B1 | ANTIBIOTIC INTERMEDIATES | ELI LILLY AND COMPANY (US) | 1993-09-08 | — | — | EP | disclosed |
| US-4772694-A | Chiral 3-(1,2,5-trisubstituted imidazolidinone) azetidinone antibiotic intermediates | ELI LILLY AND COMPANY (US) | 1988-09-20 | — | — | US | disclosed |
| EP-0254578-A1 | Antibiotic intermediates | ELI LILLY AND COMPANY (US) | 1988-01-27 | — | — | EP | disclosed |