SCHEMBL9519052

SCHEMBL9519052

CCOC(=O)c1ccc(C=C(Br)Br)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.58
CA2 P00918 3/20 0.58
CA12 O43570 2/20 0.58
CA7 P43166 2/20 0.58
CA9 Q16790 2/20 0.58
CA14 Q9ULX7 2/20 0.58
ESR1 P03372 1/20 0.58
ESR2 Q92731 1/20 0.58
LMNA P02545 2/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
MAOA P21397 1/20 0.56
HPGD P15428 4/20 0.50
HTT P42858 2/20 0.50
TSHR P16473 1/20 0.50
MAPT P10636 5/20 0.49
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
CASP3 P42574 1/20 0.49
TRPV1 Q8NER1 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12572262 0.84 CA1 (0.59) CA1CA2CA12CA7CA9
SCHEMBL17152667 0.83 CA12 (0.54) CA1CA2CA12CA7CA9
SCHEMBL2567047 0.82 LMNA (0.56) CA1CA2CA12CA7CA9
SCHEMBL2567045 0.82 LMNA (0.56) CA1CA2CA12CA7CA9
SCHEMBL10618582 0.82 CA1 (0.66) CA1CA2CA12CA7CA9
SCHEMBL9717146 0.82 CA1 (0.66) CA1CA2CA12CA7CA9
SCHEMBL11616195 0.82 CA1 (0.66) CA1CA2CA12CA7CA9
SCHEMBL9717141 0.82 CA1 (0.66) CA1CA2CA12CA7CA9
SCHEMBL87450 0.81 CA1 (0.83) CA1CA2CA12CA7CA9
SCHEMBL402110 0.80 ALDH1A1 (0.63) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0369762-B1 Pesticides ROUSSEL UCLAF (FR) 1993-12-29 EP disclosed
US-5202356-A Insecticides, miticides THE WELLCOME FOUNDATION LIMITED (GB) 1993-04-13 US disclosed
EP-0369762-A1 Pesticides ROUSSEL-UCLAF (FR) 1990-05-23 EP disclosed