Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517144 | 0.89 | PTPN1 (0.51) | ALDH1A1CYP2C9CA12CA1CA2 | |
| SCHEMBL9518001 | 0.88 | SMN1; SMN2 (0.55) | ALDH1A1P4HTMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL9517002 | 0.87 | ATM (0.49) | ALDH1A1ATMEGFRP4HTMCYP1A2 | |
| SCHEMBL9515532 | 0.85 | P4HTM (0.61) | EGFRP4HTM | |
| SCHEMBL9515461 | 0.84 | P4HTM (0.62) | EGFRP4HTMHTTCA1CA2 | |
| SCHEMBL9137568 | 0.81 | P4HTM (0.55) | ALDH1A1ATMEGFRP4HTMCYP1A2 | |
| SCHEMBL9140990 | 0.81 | P4HTM (0.66) | ATMEGFRP4HTM | |
| SCHEMBL9516185 | 0.80 | EGFR (0.57) | EGFRP4HTM | |
| SCHEMBL9516250 | 0.80 | CA2 (0.46) | ALDH1A1EGFRP4HTMCYP2C9CA2 | |
| SCHEMBL9517186 | 0.80 | BCL2L1 (0.54) | EGFRP4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |