Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.61 |
| ▸ | PTAFR | P25105 | 14/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520702 | 1.00 | TBXAS1 (0.61) | TBXAS1PTAFRKMT2ATBXA2R | |
| SCHEMBL9523136 | 0.88 | CES2 (0.53) | TBXAS1PTAFRKMT2A | |
| SCHEMBL9522407 | 0.88 | CES2 (0.53) | TBXAS1PTAFRKMT2A | |
| SCHEMBL9521346 | 0.86 | CA1 (0.49) | PTAFR | |
| Bicarbonate SCHEMBL9520704 | 0.84 | TBXAS1 (0.58) | TBXAS1PTAFRKMT2A | |
| SCHEMBL10398993 | 0.84 | PTAFR (0.60) | TBXAS1PTAFRKMT2A | |
| SCHEMBL10398976 | 0.84 | PTAFR (0.60) | TBXAS1PTAFRKMT2A | |
| Bicarbonate SCHEMBL9519216 | 0.84 | TBXAS1 (0.58) | TBXAS1PTAFRKMT2A | |
| SCHEMBL10398977 | 0.84 | PTAFR (0.60) | TBXAS1PTAFRKMT2A | |
| SCHEMBL10398227 | 0.81 | PTAFR (0.62) | TBXAS1PTAFRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299379-B1 | PENTADIENAMIDE PAF-ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1993-04-21 | — | — | EP | disclosed |
| EP-0299379-A1 | Pentadienamide PAF-antagonists | F. HOFFMANN-LA ROCHE AG (CH) | 1989-01-18 | — | — | EP | disclosed |