Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795094 | 0.94 | ALDH1A1 (0.37) | ALDH1A1MAPTHPGDTDP1CCR5 | |
| SCHEMBL9520276 | 0.92 | ALDH1A1 (0.37) | ALDH1A1MAPTHPGDTDP1CCR5 | |
| SCHEMBL9794987 | 0.91 | ALDH1A1 (0.39) | ALDH1A1MAPTHPGDTDP1CCR5 | |
| SCHEMBL9522357 | 0.90 | CYP19A1 (0.36) | ALDH1A1MAPTHPGDTDP1CCR5 | |
| SCHEMBL9522440 | 0.89 | TDP1 (0.38) | ALDH1A1MAPTHPGDTDP1CCR5 | |
| SCHEMBL9519366 | 0.89 | DPP8 (0.42) | ALDH1A1MAPTHPGDTDP1CCR5 | |
| SCHEMBL7805407 | 0.89 | ALDH1A1 (0.41) | ALDH1A1MAPTHPGDTDP1CCR5 | |
| SCHEMBL9519220 | 0.89 | ALDH1A1 (0.37) | ALDH1A1MAPTHPGDTDP1CCR5 | |
| SCHEMBL9795051 | 0.88 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDTDP1CCR5 | |
| SCHEMBL9520780 | 0.88 | DPP8 (0.36) | ALDH1A1MAPTHPGDTDP1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280771-B1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-28 | — | — | EP | disclosed |
| US-5061804-A | 3-thiopyrrolidine as chemical intermediates | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-29 | — | — | US | disclosed |
| US-4983596-A | Microbiocides; for treatment of infectious diseases | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1991-01-08 | — | — | US | disclosed |
| US-4963543-A | BACTERICIDES, TREATING INFECTIOUS DISEASES; THIENAMYCINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0341557-A1 | 3-pyrrolidinylthio-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylic acid derivatives and their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-11-15 | — | — | EP | disclosed |
| EP-0280771-A1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |