Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519366 | 0.93 | DPP8 (0.42) | DPP8DPP9MAPTRAB9ACYP3A4 | |
| SCHEMBL9522357 | 0.90 | CYP19A1 (0.36) | DPP8DPP9MAPTRAB9ACYP3A4 | |
| SCHEMBL9520276 | 0.89 | ALDH1A1 (0.37) | MAPTRAB9AALDH1A1HPGDNPC1 | |
| SCHEMBL9519224 | 0.88 | ALDH1A1 (0.37) | MAPTALDH1A1HPGDCCR5TDP1 | |
| SCHEMBL9519415 | 0.88 | RAB9A (0.40) | MAPTRAB9ACYP3A4CYP2C9TSHR | |
| SCHEMBL9795094 | 0.88 | ALDH1A1 (0.37) | MAPTRAB9AALDH1A1HPGDNPC1 | |
| SCHEMBL9519220 | 0.88 | ALDH1A1 (0.37) | MAPTRAB9AALDH1A1HPGDNPC1 | |
| SCHEMBL9794987 | 0.86 | ALDH1A1 (0.39) | MAPTALDH1A1HPGDCCR5TDP1 | |
| SCHEMBL9519853 | 0.86 | ALDH1A1 (0.36) | DPP8DPP9MAPTRAB9ACYP3A4 | |
| SCHEMBL9519631 | 0.86 | DPP8 (0.40) | DPP8DPP9MAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272456-B1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-31 | — | — | EP | disclosed |
| US-4822787-A | 3-pyrrolidinylthio-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylic acid compounds and antimicrobial activity thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0272456-A1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-29 | — | — | EP | disclosed |