Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519114 | 0.90 | UBE2M (0.39) | ALDH1A1MAPTHPGDCCR5POLB | |
| SCHEMBL9521103 | 0.86 | ALDH1A1 (0.40) | ALDH1A1CYP1A2CYP2C19MAPTHPGD | |
| SCHEMBL9520608 | 0.86 | ALDH1A1 (0.40) | ALDH1A1CYP1A2CYP2C19MAPTHPGD | |
| SCHEMBL9790271 | 0.84 | ALDH1A1 (0.36) | ALDH1A1MAPTHPGDCCR5POLB | |
| SCHEMBL9519261 | 0.84 | ALDH1A1 (0.36) | ALDH1A1MAPTHPGDCCR5POLB | |
| SCHEMBL8922233 | 0.84 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDCCR5POLB | |
| SCHEMBL9519325 | 0.84 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDCCR5POLB | |
| SCHEMBL8691844 | 0.84 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDCCR5POLB | |
| SCHEMBL9518858 | 0.83 | ALDH1A1 (0.34) | ALDH1A1MAPTHPGDCCR5POLB | |
| SCHEMBL8923969 | 0.83 | ALDH1A1 (0.37) | ALDH1A1MAPTHPGDCCR5POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280771-B1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-28 | — | — | EP | disclosed |
| US-5061804-A | 3-thiopyrrolidine as chemical intermediates | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-29 | — | — | US | disclosed |
| US-4963543-A | BACTERICIDES, TREATING INFECTIOUS DISEASES; THIENAMYCINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0280771-A1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |