Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.43 |
| ▸ | CDH1 | P12830 | 1/20 | 0.43 |
| ▸ | APC | P25054 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28105987 | 0.86 | ALPL (0.38) | CA12ALPLNOTUMMAP2K4CDH1 | |
| SCHEMBL415485 | 0.84 | KDM4E (0.55) | ALPLMAP2K4ALOX15ALDH1A1SMN1; SMN2 | |
| SCHEMBL23294328 | 0.83 | KMO (0.42) | CA12ALPLNOTUMF7F3 | |
| SCHEMBL15750438 | 0.83 | CA12 (0.45) | CA12ALPLNOTUMMAP2K4MAPK14 | |
| SCHEMBL16974002 | 0.83 | SMN1; SMN2 (0.46) | ALPLMAP2K4RAB9ANPC1ALDH1A1 | |
| SCHEMBL23294452 | 0.82 | KMO (0.47) | CASP1DHODHKMO | |
| Ethylene SCHEMBL27448159 | 0.81 | KDM4E (0.51) | ALPLMAP2K4ALOX15ALDH1A1SMN1; SMN2 | |
| SCHEMBL1729990 | 0.79 | DHODH (0.49) | KDM4EDHODHLMNA | |
| SCHEMBL6086418 | 0.78 | TDP1 (0.46) | NOTUMRAB9AALOX15ALDH1A1SMN1; SMN2 | |
| SCHEMBL15015643 | 0.74 | AKT1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104271565-B | Amide pyridine derivatives and use thereof | 田边三菱制药株式会社 | 2016-09-28 | — | — | CN | disclosed |
| CN-104271565-A | Amide pyridine derivatives and use thereof | MITSUBISHI TANABE PHARMA CORP | 2015-01-07 | — | — | CN | disclosed |
| EP-0540614-A1 | 3-(1-SUBSTITUTEDPYRAZOYL)-2-OXINDOLE DERIVATIVES. | PFIZER (US) | 1993-05-12 | — | — | EP | disclosed |