Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 1/20 | 0.34 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520697 | 0.92 | DPP8 (0.46) | DPP8DPP9TDP1ALDH1A1MAPT | |
| SCHEMBL9519874 | 0.88 | RAB9A (0.39) | DPP8DPP9RAB9ANPC1TDP1 | |
| SCHEMBL9518914 | 0.87 | TDP1 (0.40) | RAB9ANPC1TDP1ALDH1A1MAPT | |
| SCHEMBL9520673 | 0.86 | ECE1 (0.37) | DPP8DPP9RAB9ANPC1TDP1 | |
| SCHEMBL9794972 | 0.86 | TDP1 (0.39) | RAB9ANPC1TDP1ALDH1A1MAPT | |
| SCHEMBL9519480 | 0.86 | RAB9A (0.40) | DPP8DPP9RAB9ANPC1TDP1 | |
| SCHEMBL9519207 | 0.86 | CYP19A1 (0.37) | DPP8DPP9TDP1ALDH1A1MAPT | |
| SCHEMBL9520780 | 0.86 | DPP8 (0.36) | DPP8DPP9RAB9ANPC1TDP1 | |
| SCHEMBL9519405 | 0.85 | DPP8 (0.40) | DPP8DPP9RAB9ANPC1TDP1 | |
| SCHEMBL10370916 | 0.85 | RAB9A (0.42) | DPP8DPP9RAB9ANPC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272456-B1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-31 | — | — | EP | disclosed |
| US-4822787-A | 3-pyrrolidinylthio-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylic acid compounds and antimicrobial activity thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0272456-A1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-29 | — | — | EP | disclosed |