Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10520465 | 0.90 | ALDH1A1 (0.37) | ALDH1A1MAPTHPGDTDP1HTT | |
| SCHEMBL9519485 | 0.87 | SMN1; SMN2 (0.40) | RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5723979 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MAPTHPGDTDP1HTT | |
| SCHEMBL9794968 | 0.78 | ALDH1A1 (0.40) | ALDH1A1MAPTHPGDTDP1HTR2A | |
| SCHEMBL9462569 | 0.77 | ALDH1A1 (0.37) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL9462194 | 0.77 | ALDH1A1 (0.37) | ALDH1A1MAPTHPGDTDP1HTR2A | |
| SCHEMBL10519467 | 0.77 | ALDH1A1 (0.35) | ALDH1A1MAPTHPGDTDP1HTR2A | |
| SCHEMBL9462451 | 0.77 | ALDH1A1 (0.37) | ALDH1A1MAPTHPGDTDP1HTR2A | |
| SCHEMBL9466187 | 0.77 | ALDH1A1 (0.37) | ALDH1A1MAPTHPGDTDP1HTR2A | |
| SCHEMBL8582819 | 0.76 | CYP19A1 (0.39) | ALDH1A1MAPTTDP1HTR2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272456-B1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-31 | — | — | EP | disclosed |
| US-4822787-A | 3-pyrrolidinylthio-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylic acid compounds and antimicrobial activity thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0272456-A1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-29 | — | — | EP | disclosed |