Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 5/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.64 |
| ▸ | LGALS3 | P17931 | 9/20 | 0.59 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.52 |
| ▸ | OGA | O60502 | 1/20 | 0.47 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.46 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.46 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.46 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.46 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25084120 | 1.00 | LGALS8 (0.66) | LGALS8SLC6A2LGALS3LGALS9OGA | |
| SCHEMBL16099956 | 1.00 | LGALS8 (0.66) | LGALS8SLC6A2LGALS3LGALS9OGA | |
| SCHEMBL20658674 | 1.00 | LGALS8 (0.66) | LGALS8SLC6A2LGALS3LGALS9OGA | |
| SCHEMBL20671054 | 1.00 | LGALS8 (0.66) | LGALS8SLC6A2LGALS3LGALS9OGA | |
| SCHEMBL9847337 | 1.00 | LGALS8 (0.66) | LGALS8SLC6A2LGALS3LGALS9OGA | |
| SCHEMBL8566966 | 0.93 | LGALS8 (0.61) | LGALS8SLC6A2LGALS3LGALS9OGA | |
| SCHEMBL8566963 | 0.93 | LGALS8 (0.61) | LGALS8SLC6A2LGALS3LGALS9OGA | |
| SCHEMBL14747275 | 0.93 | LGALS8 (0.61) | LGALS8SLC6A2LGALS3LGALS9OGA | |
| SCHEMBL21706804 | 0.92 | LGALS8 (0.60) | LGALS8SLC6A2LGALS3LGALS9OGA | |
| SCHEMBL7152294 | 0.92 | LGALS8 (0.60) | LGALS8SLC6A2LGALS3LGALS9OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302253-B1 | 3-DEMETHYL-4-FLUORO-MEVALONIC-ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS BASED ON THOSE COMPOUNDS, THEIR USE AND INTERMEDIATES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-04-07 | — | — | EP | disclosed |
| US-4898868-A | ANTICHOLESTEROL AGENTS; LACTONE OR FREE ACID FORM | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-02-06 | — | — | US | disclosed |