Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.37 |
| ▸ | GNRHR | P30968 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8116760 | 0.83 | STAT3 (0.62) | STAT3HTTALDH1A1HPGDKDM4E | |
| SCHEMBL1345135 | 0.80 | GSK3B (0.50) | STAT3HTTALDH1A1HPGDLMNA | |
| SCHEMBL7858504 | 0.79 | HTT (0.48) | STAT3HTTALDH1A1HPGDLMNA | |
| SCHEMBL7010638 | 0.78 | HTT (0.47) | STAT3HTTALDH1A1HPGDLMNA | |
| SCHEMBL9268466 | 0.78 | STAT3 (0.43) | STAT3HTTALDH1A1HPGDLMNA | |
| SCHEMBL7861222 | 0.76 | HTT (0.45) | STAT3HTTALDH1A1HPGDLMNA | |
| SCHEMBL9032260 | 0.74 | ALDH1A1 (0.40) | STAT3HTTALDH1A1HPGDLMNA | |
| SCHEMBL25069770 | 0.73 | ALDH1A1 (0.46) | STAT3HTTALDH1A1HPGDLMNA | |
| SCHEMBL1243138 | 0.73 | LMNA (0.46) | STAT3HTTALDH1A1HPGDLMNA | |
| SCHEMBL10723280 | 0.73 | TDP1 (0.37) | STAT3HTTALDH1A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347851-B1 | Quinolonecarboxylic acids | SHIONOGI & CO (JP) | 1993-11-10 | — | — | EP | disclosed |