SCHEMBL952019

SCHEMBL952019

C=CC(=O)NC(C)(C)C(CO)OC

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
TSHR P16473 3/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
MAPK1 P28482 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TGM2 P21980 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21728873 0.77 TSHR (0.42) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL25563686 0.74 ALDH1A1 (0.41) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL137801 0.72 TSHR (0.45) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL174734 0.71 TSHR (0.48) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL22773432 0.71 ALDH1A1 (0.41) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL21439808 0.70 TSHR (0.46) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL27582105 0.69 TSHR (0.33) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL27512565 0.68 ALDH1A1 (0.42) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL7612005 0.67 ALDH1A1 (0.53) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR
SCHEMBL7617237 0.67 ALDH1A1 (0.44) ALDH1A1CYP3A4CYP2C9CYP2C19TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2259803-B2 DEVICE FOR PROMOTION OF HEMOSTASIS AND/OR WOUND HEALING FERROSAN MEDICAL DEVICES AS (DK) 2019-03-13 EP disclosed
US-9533069-B2 Device for promotion of hemostasis and/or wound healing Ferrosan Medical Devices A/S (DK) 2017-01-03 US disclosed
EP-1020195-B2 Wound dressing JENTEC INC (US) 2016-09-14 EP disclosed
US-20140220130-A1 Device For Promotion Of Hemostasis And/or Wound Healing Ferrosan Medical Devices A/S (DK) 2014-08-07 US disclosed
US-8642831-B2 Device for promotion of hemostasis and/or wound healing Ferrosan Medical Devices A/S (DK) 2014-02-04 US disclosed
US-20130029030-A1 METHOD FOR PROMOTION OF HEMOSTASIS AND/OR WOUND HEALING Ferrosan Medical Devices A/S (DK) 2013-01-31 US disclosed
CN-102905732-A A method for promotion of hemostasis and/or wound healing FERROSAN MEDICAL DEVICES AS 2013-01-30 CN disclosed
EP-2547371-A1 A method for promotion of hemostasis and/or wound healing Ferrosan Medical Devices A/S (DK) 2013-01-23 EP disclosed
EP-2259803-B1 DEVICE FOR PROMOTION OF HEMOSTASIS AND/OR WOUND HEALING FERROSAN MEDICAL DEVICES AS (DK) 2012-09-05 EP disclosed
WO-2011113436-A1 A method for promotion of hemostasis and/or wound healing Ferrosan Medical Devices A/S (DK) 2011-09-22 WO disclosed
US-4548990-A HIGH DEGREE OF SWELLING IN ORGANIC SOLVENTS CIBA-GEIGY CORPORATION (US) 1985-10-22 US disclosed
EP-0140828-A2 Cross-linked porous polymers for controlled drug release CIBA-GEIGY AG (CH) 1985-05-08 EP disclosed
EP-0000507-B1 PROCESS FOR THE PRODUCTION OF HYDROGELS IN THE FORM OF SPHERICALLY SHAPED BEADS WITH LARGER DIAMETERS CIBA-GEIGY AG (CH) 1982-09-29 EP disclosed
US-4304591-A A HIGH-STRENGTH GEL OF MALEIMIDE-MODIFIED POLYOXYPROPYLENE OR -TETRAMETHYLENE GLYCOL CROSSLINKED BY A WATER-SOLUBLE OLEFIN; SUSTAINED RELEASE CIBA-GEIGY CORPORATION (US) 1981-12-08 US disclosed
US-4277582-A MEMBRANES AND CARRIERS FOR SUSTAINED RELEASE CIBA-GEIGY CORPORATION (US) 1981-07-07 US disclosed
US-4224427-A HYDROPHILIC MONOMER, POLYOLEFINIC MACROMER CROSSLINKER, METAL HYDROXIDE GEL CIBA-GEIGY CORPORATION (US) 1980-09-23 US disclosed
US-4192827-A IN A DELAMINATED MATRIX OF A TRANSITITION METAL DICHALCOGENIDE CIBA-GEIGY CORPORATION (US) 1980-03-11 US disclosed
US-4177056-A CROSSLINKED; SUSTAINED RELEASE CIBA-GEIGY CORPORATION (US) 1979-12-04 US disclosed
EP-0000507-A1 Process for the production of hydrogels in the form of spherically shaped beads with larger diameters CIBA-GEIGY AG (CH) 1979-02-07 EP disclosed
US-4136250-A CROSSLINKED, ADDITION MONOMER OR POLYMER CIBA-GEIGY CORPORATION (US) 1979-01-23 US disclosed