Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 15/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520911 | 0.95 | MAPT (0.63) | FAAHKDM4EMAPTSMN1; SMN2NPC1 | |
| SCHEMBL6737613 | 0.92 | FAAH (0.66) | FAAHKDM4EMAPT | |
| SCHEMBL10410350 | 0.85 | GAA (0.54) | FAAHKDM4EMAPTSMN1; SMN2RAB9A | |
| SCHEMBL9520617 | 0.84 | FAAH (0.55) | FAAHKDM4EMAPT | |
| SCHEMBL9520601 | 0.84 | FAAH (0.62) | FAAHKDM4EMAPTSMN1; SMN2NPC1 | |
| SCHEMBL9519747 | 0.81 | FAAH (0.65) | FAAHMAPTSMN1; SMN2RAB9A | |
| SCHEMBL17460106 | 0.78 | FAAH (0.58) | FAAHKDM4EMAPTSMN1; SMN2NPC1 | |
| SCHEMBL6732909 | 0.77 | KDM4E (0.50) | FAAHKDM4EMAPTSMN1; SMN2TSHR | |
| SCHEMBL6318888 | 0.77 | S1PR5 (0.53) | FAAHSMN1; SMN2TSHR | |
| SCHEMBL10410772 | 0.76 | POLB (0.54) | KDM4EMAPTSMN1; SMN2NPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308843-B1 | Bispidin derivatives as class III antiarrhythmics | BASF AG (DE) | 1993-12-15 | — | — | EP | claimed |
| EP-0308843-B1 | Bispidin derivatives as class III antiarrhythmics | BASF AG (DE) | 1993-12-15 | — | — | EP | disclosed |
| US-4959373-A | Bispidine derivatives as class III antiarrhythmic agents | BASF AKTIENGESELLSCHAFT (DE) | 1990-09-25 | — | — | US | disclosed |
| EP-0308843-A2 | Bispidin derivatives as class III antiarrhythmics | BASF Aktiengesellschaft (DE) | 1989-03-29 | — | — | EP | disclosed |