Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.62 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | CA9 | Q16790 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.51 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6737613 | 0.91 | FAAH (0.66) | FAAHGRIN2BCA12CA2CA9 | |
| SCHEMBL9520911 | 0.89 | MAPT (0.63) | FAAHCA12CA2CA9KDM4E | |
| SCHEMBL9520617 | 0.88 | FAAH (0.55) | FAAHGRIN2BCA12CA2CA9 | |
| SCHEMBL9519747 | 0.87 | FAAH (0.65) | FAAHGRIN2BCA12CA2CA9 | |
| SCHEMBL9520201 | 0.84 | FAAH (0.69) | FAAHKDM4EMAPTSMN1; SMN2NPC1 | |
| SCHEMBL9521948 | 0.82 | ALDH1A1 (0.50) | KDM4ESMN1; SMN2MAPK1ALDH1A1POLB | |
| SCHEMBL6732909 | 0.81 | KDM4E (0.50) | FAAHKDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6733582 | 0.80 | CYP3A4 (0.46) | FAAHKDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL10410350 | 0.79 | GAA (0.54) | FAAHKDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1895069 | 0.79 | CYP2D6 (0.54) | SMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308843-B1 | Bispidin derivatives as class III antiarrhythmics | BASF AG (DE) | 1993-12-15 | — | — | EP | disclosed |
| US-4959373-A | Bispidine derivatives as class III antiarrhythmic agents | BASF AKTIENGESELLSCHAFT (DE) | 1990-09-25 | — | — | US | disclosed |
| EP-0308843-A2 | Bispidin derivatives as class III antiarrhythmics | BASF Aktiengesellschaft (DE) | 1989-03-29 | — | — | EP | disclosed |