Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11043580 | 0.87 | RAB9A (0.59) | RAB9AIDO1ALDH1A1MAPTAKR1C3 | |
| SCHEMBL1555636 | 0.86 | ALDH1A1 (0.59) | RAB9AIDO1ALDH1A1MAPTAKR1C3 | |
| SCHEMBL7729899 | 0.85 | ALDH1A1 (0.58) | RAB9AIDO1ALDH1A1MAPTAKR1C3 | |
| SCHEMBL5235557 | 0.85 | IDO1 (0.56) | RAB9AIDO1ALDH1A1MAPTAKR1C3 | |
| SCHEMBL11383154 | 0.84 | RAB9A (0.56) | RAB9AIDO1ALDH1A1MAPTAKR1C3 | |
| SCHEMBL11040897 | 0.84 | RAB9A (0.55) | RAB9AIDO1ALDH1A1MAPTAKR1C3 | |
| SCHEMBL6141237 | 0.83 | ALDH1A1 (0.56) | RAB9AIDO1ALDH1A1MAPTAKR1C3 | |
| Water SCHEMBL8424505 | 0.83 | RAB9A (0.54) | RAB9AIDO1ALDH1A1MAPTAKR1C3 | |
| SCHEMBL11094410 | 0.83 | ALDH1A1 (0.56) | RAB9AIDO1ALDH1A1MAPTAKR1C3 | |
| SCHEMBL15388876 | 0.83 | RAB9A (0.61) | RAB9AIDO1ALDH1A1MAPTAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254578-B1 | ANTIBIOTIC INTERMEDIATES | ELI LILLY AND COMPANY (US) | 1993-09-08 | — | — | EP | disclosed |
| EP-0237027-B1 | 6-(DISUBSTITUTED AMINO) CARBAPENAM COMPOUNDS | Sanraku Incorporated (JP) | 1992-06-10 | — | — | EP | disclosed |
| US-4996314-A | 6-(disubstituted amino)carbapenem compounds | SANRAKU INCORPORATED (JP) | 1991-02-26 | — | — | US | disclosed |
| US-4992544-A | Intermediates for b-lactam antibiotics and b-lactamase inhibitor | UNIVERSITY OF NOTRE DAME DU LAC (US) | 1991-02-12 | — | — | US | disclosed |
| US-4820815-A | USEFUL AS ANTIBACTERIALS OR TO FORM FUSED BICYCLIC B-LACTAM ANTIBIOTICS LIKE CARBAPENEMS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 1989-04-11 | — | — | US | disclosed |
| US-4812563-A | ANTIBIOTICS | SANRAKU INCORPORATED (JP) | 1989-03-14 | — | — | US | disclosed |
| EP-0306266-A1 | Azetidinone n-phosphonomethyl esters | THE UNIVERSITY OF NOTRE DAME DU LAC (US) | 1989-03-08 | — | — | EP | disclosed |
| US-4772694-A | Chiral 3-(1,2,5-trisubstituted imidazolidinone) azetidinone antibiotic intermediates | ELI LILLY AND COMPANY (US) | 1988-09-20 | — | — | US | disclosed |
| EP-0254578-A1 | Antibiotic intermediates | ELI LILLY AND COMPANY (US) | 1988-01-27 | — | — | EP | disclosed |
| EP-0237027-A2 | 6-(Disubstituted amino) carbapenam compounds | Sanraku Incorporated (JP) | 1987-09-16 | — | — | EP | disclosed |
| US-4539152-A | INTERMEDIATES FOR THIENAMYCIN ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-09-03 | — | — | US | disclosed |
| EP-0035689-B1 | 4-SUBSTITUTED-2-OXOAZETIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION, AND THEIR USE FOR PREPARING ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-12-19 | — | — | EP | disclosed |
| EP-0040408-B1 | BETA-LACTAM COMPOUNDS AND PROCESS FOR PRODUCTION THEREOF | SANRAKU-OCEAN CO., LTD. (JP) | 1984-08-29 | — | — | EP | disclosed |
| EP-0105227-A1 | Process for producing beta-lactam compounds, and intermediates useful for their production | Sanraku Incorporated (JP) | 1984-04-11 | — | — | EP | disclosed |
| US-4383945-A | 4-Substituted-2-oxoazetidine compounds and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-05-17 | — | — | US | disclosed |
| EP-0040408-A1 | Beta-lactam compounds and process for production thereof | SANRAKU-OCEAN CO., LTD. (JP) | 1981-11-25 | — | — | EP | disclosed |
| EP-0035689-A1 | 4-Substituted-2-oxoazetidine compounds, processes for their preparation, and their use for preparing antibiotics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-09-16 | — | — | EP | disclosed |