Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19345044 | 0.74 | ALDH1A1 (0.35) | TDP1FFAR3ALDH1A1SOAT1 | |
| SCHEMBL4145027 | 0.74 | TDP1 (0.35) | TDP1FFAR3ALDH1A1SOAT1 | |
| SCHEMBL3972457 | 0.74 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL2757994 | 0.72 | TDP1 (0.40) | TDP1FFAR3ALDH1A1SOAT1 | |
| SCHEMBL28553457 | 0.72 | ALDH1A1 (0.42) | ALDH1A1SOAT1 | |
| SCHEMBL28363858 | 0.70 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL23343785 | 0.70 | TDP1 (0.32) | TDP1FFAR3ALDH1A1SOAT1 | |
| SCHEMBL8403036 | 0.70 | LMNA (0.33) | TDP1FFAR3ALDH1A1SOAT1 | |
| SCHEMBL3283392 | 0.69 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL4153230 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248594-B1 | Pharmacologically active 1,5-diaryl-3-substituted-pyrazoles and method for synthesizing the same | ORTHO PHARMA CORP (US) | 1993-11-24 | — | — | EP | claimed |
| EP-0248594-A2 | Pharmacologically active 1,5-diaryl-3-substituted-pyrazoles and method for synthesizing the same | ORTHO PHARMACEUTICAL CORPORATION (US) | 1987-12-09 | — | — | EP | claimed |
| EP-0248594-B1 | Pharmacologically active 1,5-diaryl-3-substituted-pyrazoles and method for synthesizing the same | ORTHO PHARMA CORP (US) | 1993-11-24 | — | — | EP | disclosed |