Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521718 | 0.89 | CYP3A4 (0.55) | NR1I2CYP3A4CYP2D6TDP1L3MBTL1 | |
| SCHEMBL9521817 | 0.85 | CYP3A4 (0.51) | NR1I2CYP3A4CYP2D6TDP1L3MBTL1 | |
| SCHEMBL9520549 | 0.85 | CYP3A4 (0.51) | NR1I2CYP3A4CYP2D6TDP1L3MBTL1 | |
| SCHEMBL9521541 | 0.83 | AOC3 (0.43) | NR1I2CYP3A4CYP2D6TDP1L3MBTL1 | |
| SCHEMBL9210194 | 0.81 | NR1I2 (0.53) | NR1I2CYP3A4CYP2D6TDP1L3MBTL1 | |
| SCHEMBL9520408 | 0.79 | NR1I2 (0.53) | NR1I2CYP3A4CYP2D6TDP1L3MBTL1 | |
| SCHEMBL9520598 | 0.78 | NR1I2 (0.53) | NR1I2CYP3A4CYP2D6TDP1L3MBTL1 | |
| SCHEMBL9205929 | 0.78 | NR1I2 (0.57) | NR1I2CYP3A4CYP2D6TDP1L3MBTL1 | |
| SCHEMBL9203587 | 0.77 | NR1I2 (0.56) | NR1I2CYP3A4CYP2D6TDP1L3MBTL1 | |
| SCHEMBL8137086 | 0.76 | NR1I2 (0.76) | NR1I2CYP3A4CYP2D6HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523803-A1 | 1,2,4-Oxadiazolyl-phenoxy-alkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1993-01-20 | — | — | EP | claimed |
| US-5175177-A | 1,2,4-OXADIAZOLYL-PHENOXYALKYLISOXAZOLES AND THEIR USE AS ANTIVIRAL AGENTS | STERLING DRUG INC. (US) | 1992-12-29 | — | — | US | claimed |