Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 10/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 9/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205929 | 0.92 | NR1I2 (0.57) | NR1I2CYP3A4CYP2D6SCARB1L3MBTL1 | |
| SCHEMBL9520408 | 0.88 | NR1I2 (0.53) | NR1I2CYP3A4CYP2D6PPARASCARB1 | |
| SCHEMBL9521718 | 0.88 | CYP3A4 (0.55) | NR1I2CYP3A4CYP2D6SCARB1L3MBTL1 | |
| SCHEMBL9200266 | 0.86 | NR1I2 (0.73) | NR1I2CYP3A4CYP2D6SCARB1L3MBTL1 | |
| SCHEMBL9201720 | 0.84 | CYP3A4 (0.52) | NR1I2CYP3A4CYP2D6PPARASCARB1 | |
| SCHEMBL9520549 | 0.84 | CYP3A4 (0.51) | NR1I2CYP3A4CYP2D6PPARASCARB1 | |
| SCHEMBL9521817 | 0.84 | CYP3A4 (0.51) | NR1I2CYP3A4CYP2D6PPARASCARB1 | |
| SCHEMBL9523316 | 0.82 | NR1I2 (0.54) | NR1I2CYP3A4CYP2D6L3MBTL1S1PR1 | |
| SCHEMBL9200238 | 0.82 | NR1I2 (0.48) | NR1I2CYP3A4CYP2D6PPARASCARB1 | |
| SCHEMBL9521412 | 0.82 | NR1I2 (0.68) | NR1I2CYP3A4CYP2D6SCARB1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413289-B1 | Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC (US) | 1995-02-01 | — | — | EP | disclosed |
| US-5175178-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING DRUG INC. (US) | 1992-12-29 | — | — | US | disclosed |
| EP-0413289-A2 | Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1991-02-20 | — | — | EP | disclosed |