Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521817 | 1.00 | CYP3A4 (0.51) | CYP3A4CYP2D6NR1I2L3MBTL1SCARB1 | |
| SCHEMBL9521718 | 0.96 | CYP3A4 (0.55) | CYP3A4CYP2D6NR1I2L3MBTL1SCARB1 | |
| SCHEMBL9201720 | 0.88 | CYP3A4 (0.52) | CYP3A4CYP2D6NR1I2L3MBTL1SCARB1 | |
| SCHEMBL9202945 | 0.85 | NR1I2 (0.67) | CYP3A4CYP2D6NR1I2L3MBTL1SCARB1 | |
| SCHEMBL9520566 | 0.85 | NR1I2 (0.44) | CYP3A4CYP2D6NR1I2L3MBTL1SCARB1 | |
| SCHEMBL9520408 | 0.85 | NR1I2 (0.53) | CYP3A4CYP2D6NR1I2L3MBTL1SCARB1 | |
| SCHEMBL9205929 | 0.84 | NR1I2 (0.57) | CYP3A4CYP2D6NR1I2L3MBTL1SCARB1 | |
| SCHEMBL9520598 | 0.84 | NR1I2 (0.53) | CYP3A4CYP2D6NR1I2L3MBTL1S1PR1 | |
| SCHEMBL9203587 | 0.84 | NR1I2 (0.56) | CYP3A4CYP2D6NR1I2L3MBTL1SCARB1 | |
| SCHEMBL8137086 | 0.82 | NR1I2 (0.76) | CYP3A4CYP2D6NR1I2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523803-A1 | 1,2,4-Oxadiazolyl-phenoxy-alkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1993-01-20 | — | — | EP | disclosed |