SCHEMBL9520652

SCHEMBL9520652

NS(=O)(=O)c1c(Cl)nc2n1CCS2

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 3/20 0.73
XDH P47989 2/20 0.36
LMNA P02545 1/20 0.35
MAPT P10636 4/20 0.35
GAA P10253 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
ALDH1A1 P00352 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CYP2C19 P33261 4/20 0.33
CYP2C9 P11712 3/20 0.33
CYP1A2 P05177 2/20 0.33
RECQL P46063 1/20 0.33
RAB9A P51151 1/20 0.33
POLB P06746 3/20 0.32
USP2 O75604 1/20 0.32
HPGD P15428 1/20 0.32
ALOX12 P18054 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ADORA3 P0DMS8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1590334 0.85 HTR6 (1.00) HTR6XDHLMNAMAPTGAA
SCHEMBL3875671 0.83 HTR6 (0.73) HTR6XDHLMNAMAPTGAA
SCHEMBL1590351 0.70 HTR6 (0.69) HTR6XDHLMNAMAPTGAA
SCHEMBL8124762 0.69 HTR6 (0.54) HTR6XDHLMNAMAPTGAA
SCHEMBL1590856 0.68 HTR6 (0.53) HTR6LMNAMAPTSMN1; SMN2ALDH1A1
SCHEMBL1590132 0.67 HTR6 (0.67) HTR6LMNASMN1; SMN2ALDH1A1MEN1
SCHEMBL1590218 0.67 HTR6 (0.50) HTR6MAPTGAASMN1; SMN2ALDH1A1
SCHEMBL1590451 0.67 HTR6 (0.67) HTR6LMNASMN1; SMN2ALDH1A1MEN1
SCHEMBL23991292 0.67 HTR6 (0.47) HTR6XDHLMNAMAPTGAA
SCHEMBL1591157 0.67 HTR6 (0.49) HTR6MAPTGAASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0238070-B1 Sulfonylurea compounds, their production and herbicidal use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1993-12-29 EP disclosed
US-5017212-A For rice paddies TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-05-21 US disclosed
EP-0238070-A2 Sulfonylurea compounds, their production and herbicidal use Takeda Chemical Industries, Ltd. (JP) 1987-09-23 EP disclosed