Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 5/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | PTPRF | P10586 | 1/20 | 0.34 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TCF4 | P15884 | 1/20 | 0.30 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522184 | 0.85 | ADRA1A (0.38) | ADRA1AACHEPTPRF | |
| SCHEMBL8529148 | 0.84 | ADRA1A (0.39) | ADRA1AACHEPTPRFPOLLALDH1A1 | |
| SCHEMBL8528995 | 0.75 | ADRA1A (0.43) | ADRA1AACHEPTPRFPOLLALDH1A1 | |
| SCHEMBL8903292 | 0.72 | ADRA1A (0.41) | ADRA1AACHEPOLLGAAKDM4E | |
| SCHEMBL9522309 | 0.69 | ADRA1A (0.37) | ADRA1AACHEPTPRFALDH1A1 | |
| SCHEMBL8902583 | 0.65 | ADRA1A (0.45) | ADRA1AACHEPTPRFPOLLALDH1A1 | |
| SCHEMBL27354253 | 0.64 | ADRA1A (0.41) | ADRA1AACHEPOLLALDH1A1GAA | |
| SCHEMBL13479460 | 0.63 | ADRA1A (0.55) | ADRA1AACHEPTPRFALDH1A1GAA | |
| SCHEMBL27394377 | 0.62 | ADRA1A (0.55) | ADRA1AACHEPTPRFALDH1A1GAA | |
| SCHEMBL9522522 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533744-A1 | HETEROCYCLIC ANTHRACYCLIONE AND ANTHRACYCLINE ANALOGS | BIOCHEM PHARMA INC. (CA) | 1993-03-31 | — | — | EP | disclosed |
| WO-1991019725-A2 | HETEROCYCLIC ANTHRACYCLIONE AND ANTHRACYCLINE ANALOGS | BIOCHEM PHARMA INC. (CA) | 1991-12-26 | — | — | WO | disclosed |