Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520494 | 0.85 | SIGMAR1 (0.53) | SIGMAR1ALOX5LTA4HKMT2ANPC1 | |
| SCHEMBL11669812 | 0.83 | TAAR1 (0.54) | L3MBTL1LTA4HALDH1A1KMT2AMEN1 | |
| SCHEMBL9521674 | 0.82 | SIGMAR1 (0.58) | SIGMAR1 | |
| SCHEMBL9522150 | 0.81 | KDM4E (0.50) | SIGMAR1 | |
| SCHEMBL9521166 | 0.81 | KCNH2 (0.50) | SIGMAR1 | |
| SCHEMBL9521946 | 0.81 | SIGMAR1 (0.49) | SIGMAR1KMT2ATAAR1 | |
| SCHEMBL15701715 | 0.81 | TAAR1 (0.48) | TAAR1 | |
| SCHEMBL20871345 | 0.79 | AOC3 (0.51) | SIGMAR1ALOX5TDP1L3MBTL1LTA4H | |
| SCHEMBL9520591 | 0.77 | POLB (0.46) | SIGMAR1ALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL11813263 | 0.77 | TAAR1 (0.52) | SIGMAR1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507863-A4 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | — | 1993-07-07 | — | — | EP | claimed |
| EP-0507863-A1 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1992-10-14 | — | — | EP | claimed |