SCHEMBL9520682

SCHEMBL9520682

COc1cc(NC(=O)Oc2ccccc2)nc(OC)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.52
GAA P10253 3/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
HTT P42858 2/20 0.52
KMT2A Q03164 5/20 0.50
MEN1 O00255 3/20 0.50
POLB P06746 1/20 0.47
MAPT P10636 4/20 0.46
TP53 P04637 3/20 0.45
GLA P06280 2/20 0.45
CYP1A2 P05177 2/20 0.45
KDM4E B2RXH2 2/20 0.44
HPGD P15428 1/20 0.44
ATM Q13315 1/20 0.44
NPC1 O15118 1/20 0.44
NFKB1 P19838 1/20 0.44
RAB9A P51151 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
THRB P10828 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9517392 0.86 ALDH1A1 (0.52) ALDH1A1GAASMN1; SMN2HTTKMT2A
SCHEMBL15890196 0.85 NPC1 (0.59) ALDH1A1GAASMN1; SMN2HTTKMT2A
SCHEMBL1576702 0.84 MAPT (0.59) ALDH1A1GAASMN1; SMN2HTTKMT2A
SCHEMBL59779 0.83 ALDH1A1 (0.51) ALDH1A1GAASMN1; SMN2HTTKMT2A
SCHEMBL1010432 0.81 ALDH1A1 (0.49) ALDH1A1GAASMN1; SMN2HTTKMT2A
SCHEMBL9661273 0.81 POLB (0.53) ALDH1A1GAASMN1; SMN2HTTKMT2A
SCHEMBL27408521 0.81 KDM4E (0.49) ALDH1A1SMN1; SMN2MAPTTP53GLA
SCHEMBL30925086 0.80 MAPT (0.49) ALDH1A1GAASMN1; SMN2HTTKMT2A
SCHEMBL27427330 0.80 SMN1; SMN2 (0.63) ALDH1A1GAASMN1; SMN2HTTKMT2A
SCHEMBL8533974 0.80 HTT (0.53) ALDH1A1GAASMN1; SMN2HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1042480-A None JP disclosed
CN-104151294-A Method for producing pyrimidine compound ISHIHARA SANGYO KAISHA 2014-11-19 CN disclosed
CN-102007119-B Process for producing pyrimidine compound Ishihara Sangyo Kabushiki Kaisha Ltd. (JP) 2014-10-15 CN disclosed
CN-102007119-A Process for producing pyrimidine compound ISHIHARA SANGYO KAISHA 2011-04-06 CN disclosed
CN-101291584-A Herbicide composition NISSAN CHEMICAL IND LTD (JP) 2008-10-22 CN disclosed
CN-100349517-C Fused heterocyclic sulfonylurea compound, herbicide containing the same and method of controlling weed with the same SUMITOMO CHEM TAKEDA AGRO CO (JP) 2007-11-21 CN disclosed
CN-1617666-A Fused heterocyclic sulfonylurea compound, herbicide containing the same, and method for controlling weeds using the same SUMITOMO CHEM TAKEDA AGRO CO (JP) 2005-05-18 CN disclosed
CN-1187339-C Method for producing 4,6-disubstituted 2-isocyanatopyrimidines and to their use as intermediate products for active ingredient syntheses AVENTIES CROPS SCIENCE GMBH (DE) 2005-02-02 CN disclosed
CN-1172931-C Herbicidally active pyridine sulfonyl urea derivatives LGCI��ʽ���� 2004-10-27 CN disclosed
CN-1097592-C Herbicidal sulfonamide derivatives LG CHEMICAL LTD (KR) 2003-01-01 CN disclosed
US-5017212-A For rice paddies TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-05-21 US disclosed
CN-1011309-B PROCESS FOR PREPARING SUBSTITUTED THIOPHENESULFONAMIDE AND SALTS THEREOF USED AS HERBICIDES ISHIHARA SANGYO KAISHA (JP) 1991-01-23 CN disclosed
JP-S6442480-A SULFONAMIDE BASED COMPOUND OR ITS SALT, PRODUCTION THEREOF AND HERBICIDE CONTAINING SAID COMPOUND OR SALT AS ACTIVE INGREDIENT ISHIHARA MINING & CHEMICAL CO 1989-02-14 JP disclosed
US-4727186-A PLANT GROWTH REGULATORS CIBA-GEIGY CORPORATION (US) 1988-02-23 US disclosed
CN-87102123-A Sulfonylurea compounds, their preparation and their use as herbicides 1987-10-21 CN disclosed
EP-0238070-A2 Sulfonylurea compounds, their production and herbicidal use Takeda Chemical Industries, Ltd. (JP) 1987-09-23 EP disclosed
CN-86103880-A Contain herbicide of thiophene sulfonamide compounds and preparation method thereof 1987-01-21 CN disclosed
CN-85101667-A The aminosulfonylthiophene compound that replaces and the preparation method of its esters and as the purposes of weedicide 1987-01-17 CN disclosed
US-4594097-A Herbicide CIBA-GEIGY CORPORATION (US) 1986-06-10 US disclosed
US-4537618-A PRE-AND POST-EMERGENCE HIRBICIDE CIBA GEIGY CORPORATION (US) 1985-08-27 US disclosed