Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TCF4 | P15884 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | CTH | P32929 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520944 | 0.85 | TCF4 (0.41) | TCF4CTNNB1CTHIDO1 | |
| SCHEMBL9522381 | 0.80 | KDM4E (0.34) | KDM4EALDH1A1 | |
| SCHEMBL9755801 | 0.80 | KDM4E (0.34) | TCF4CTNNB1CTHIDO1KDM4E | |
| SCHEMBL8533356 | 0.73 | TCF4 (0.38) | TCF4CTNNB1CTHIDO1KDM4E | |
| SCHEMBL9521432 | 0.71 | — | — | |
| SCHEMBL9755771 | 0.70 | BACE1 (0.32) | IDO1 | |
| SCHEMBL9521049 | 0.66 | NQO1 (0.39) | — | |
| SCHEMBL8899885 | 0.65 | AKT1 (0.40) | TCF4CTNNB1CTHIDO1 | |
| SCHEMBL10992756 | 0.60 | BACE1 (0.36) | IDO1 | |
| SCHEMBL10863131 | 0.60 | BACE1 (0.36) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533744-A1 | HETEROCYCLIC ANTHRACYCLIONE AND ANTHRACYCLINE ANALOGS | BIOCHEM PHARMA INC. (CA) | 1993-03-31 | — | — | EP | claimed |
| WO-1991019725-A2 | HETEROCYCLIC ANTHRACYCLIONE AND ANTHRACYCLINE ANALOGS | BIOCHEM PHARMA INC. (CA) | 1991-12-26 | — | — | WO | claimed |
| EP-0533744-A1 | HETEROCYCLIC ANTHRACYCLIONE AND ANTHRACYCLINE ANALOGS | BIOCHEM PHARMA INC. (CA) | 1993-03-31 | — | — | EP | disclosed |
| WO-1991019725-A2 | HETEROCYCLIC ANTHRACYCLIONE AND ANTHRACYCLINE ANALOGS | BIOCHEM PHARMA INC. (CA) | 1991-12-26 | — | — | WO | disclosed |