Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TCF4 | P15884 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | CTH | P32929 | 1/20 | 0.38 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520730 | 0.85 | TCF4 (0.32) | TCF4CTNNB1IDO1CTH | |
| SCHEMBL8533356 | 0.76 | TCF4 (0.38) | TCF4CTNNB1IDO1CTHDNMT3B | |
| SCHEMBL9755801 | 0.69 | KDM4E (0.34) | TCF4CTNNB1IDO1CTHDNMT3B | |
| SCHEMBL9521049 | 0.64 | NQO1 (0.39) | — | |
| SCHEMBL8911771 | 0.60 | MEN1 (0.33) | DHODH | |
| SCHEMBL9755771 | 0.59 | BACE1 (0.32) | IDO1AKT1DHODH | |
| SCHEMBL3981018 | 0.59 | LMNA (0.43) | — | |
| SCHEMBL29941346 | 0.59 | LMNA (0.43) | — | |
| SCHEMBL29364188 | 0.59 | MEN1 (0.56) | TDP2 | |
| SCHEMBL354514 | 0.59 | MEN1 (0.56) | TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533744-A1 | HETEROCYCLIC ANTHRACYCLIONE AND ANTHRACYCLINE ANALOGS | BIOCHEM PHARMA INC. (CA) | 1993-03-31 | — | — | EP | claimed |
| WO-1991019725-A2 | HETEROCYCLIC ANTHRACYCLIONE AND ANTHRACYCLINE ANALOGS | BIOCHEM PHARMA INC. (CA) | 1991-12-26 | — | — | WO | claimed |