Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520561 | 1.00 | SLC6A3 (0.41) | SLC6A3ITGA4ITGB7CNR1CNR2 | |
| SCHEMBL9491490 | 1.00 | SLC6A3 (0.41) | SLC6A3ITGA4ITGB7CNR1CNR2 | |
| SCHEMBL9491497 | 1.00 | SLC6A3 (0.41) | SLC6A3ITGA4ITGB7CNR1CNR2 | |
| SCHEMBL9520568 | 1.00 | SLC6A3 (0.41) | SLC6A3ITGA4ITGB7CNR1CNR2 | |
| SCHEMBL9491793 | 0.90 | ITGA4 (0.41) | SLC6A3ITGA4ITGB7CNR1CNR2 | |
| SCHEMBL9523184 | 0.90 | ITGA4 (0.41) | SLC6A3ITGA4ITGB7CNR1CNR2 | |
| SCHEMBL9520185 | 0.90 | ITGA4 (0.41) | SLC6A3ITGA4ITGB7CNR1CNR2 | |
| SCHEMBL9491487 | 0.90 | ITGA4 (0.41) | SLC6A3ITGA4ITGB7CNR1CNR2 | |
| SCHEMBL9520177 | 0.90 | ITGA4 (0.41) | SLC6A3ITGA4ITGB7CNR1CNR2 | |
| SCHEMBL9492713 | 0.83 | SLC6A3 (0.52) | SLC6A3ITGA4ITGB7CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0390693-B1 | THIOFORMAMIDE DERIVATIVES | RHONE-POULENC SANTE (FR) | 1993-08-25 | — | — | EP | disclosed |
| EP-0390693-A1 | Thioformamide derivatives | RHONE-POULENC SANTE (FR) | 1990-10-03 | — | — | EP | disclosed |