Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7668277 | 0.75 | KMT2A (0.38) | KMT2AL3MBTL1ALDH1A1CASP3SENP8 | |
| SCHEMBL7660312 | 0.75 | TDP1 (0.40) | KMT2AL3MBTL1ALDH1A1CASP3SENP8 | |
| SCHEMBL12578617 | 0.74 | L3MBTL1 (0.43) | KMT2AL3MBTL1ALDH1A1CASP3SENP8 | |
| SCHEMBL11982126 | 0.71 | L3MBTL1 (0.46) | KMT2AL3MBTL1ALDH1A1CASP3SENP8 | |
| SCHEMBL7672046 | 0.70 | L3MBTL1 (0.36) | KMT2AL3MBTL1ALDH1A1CASP3SENP8 | |
| SCHEMBL1845718 | 0.70 | L3MBTL1 (0.44) | KMT2AL3MBTL1ALDH1A1CASP3SENP8 | |
| SCHEMBL4065887 | 0.70 | KMT2A (0.47) | KMT2AL3MBTL1ALDH1A1CASP3SENP8 | |
| SCHEMBL7668271 | 0.69 | KMT2A (0.43) | KMT2AL3MBTL1ALDH1A1CASP3SENP8 | |
| SCHEMBL19323878 | 0.68 | KMT2A (0.56) | KMT2AL3MBTL1ALDH1A1CASP3SENP8 | |
| SCHEMBL247545 | 0.67 | ALDH1A1 (0.48) | KMT2AL3MBTL1ALDH1A1CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302389-B1 | Alpha-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-12-22 | — | — | EP | disclosed |
| EP-0302389-A2 | Alpha-unsaturated amines, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-08 | — | — | EP | disclosed |