Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10575533 | 0.85 | HCRTR1 (0.42) | SMN1; SMN2ADORA2ALMNAHCRTR1HCRTR2 | |
| SCHEMBL9522293 | 0.83 | MEN1 (0.49) | SMN1; SMN2ADORA2ALMNATSHRHCRTR1 | |
| SCHEMBL961121 | 0.81 | ADORA2A (0.47) | ADORA2ALMNAHCRTR1HCRTR2HTT | |
| SCHEMBL9521243 | 0.73 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNATSHRHTTNPSR1 | |
| SCHEMBL18005401 | 0.71 | TSHR (0.51) | SMN1; SMN2LMNATSHRHTTNPSR1 | |
| SCHEMBL10677397 | 0.71 | ADORA2A (0.40) | ADORA2ALMNAHTTADORA3ADORA2B | |
| SCHEMBL13966673 | 0.70 | SMN1; SMN2 (0.61) | SMN1; SMN2LMNAHTTMAPK1KDM4E | |
| SCHEMBL8363953 | 0.69 | ADORA2A (0.44) | ADORA2ALMNAHCRTR1HCRTR2HTT | |
| SCHEMBL28870957 | 0.69 | HTT (0.62) | ADORA2ALMNAHTTADORA3ADORA2B | |
| SCHEMBL30620582 | 0.69 | KDM4E (0.62) | SMN1; SMN2ADORA2ALMNAHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257850-B1 | Pyrimidine derivatives | NISSIN FOOD PRODUCTS LTD (JP) | 1993-12-08 | — | — | EP | claimed |
| US-4849424-A | ANTIULCER AGENTS | NISSIN SHOKUHIN KABUSHIKI KAISHA (JP) | 1989-07-18 | — | — | US | claimed |
| EP-0257850-A2 | Pyrimidine derivatives | NISSIN SHOKUHIN KABUSHIKI KAISHA doing international business as NISSIN FOOD PRODUCTS CO., LTD. (JP) | 1988-03-02 | — | — | EP | claimed |
| EP-0257850-B1 | Pyrimidine derivatives | NISSIN FOOD PRODUCTS LTD (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-4849424-A | ANTIULCER AGENTS | NISSIN SHOKUHIN KABUSHIKI KAISHA (JP) | 1989-07-18 | — | — | US | disclosed |
| EP-0257850-A2 | Pyrimidine derivatives | NISSIN SHOKUHIN KABUSHIKI KAISHA doing international business as NISSIN FOOD PRODUCTS CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |